Goldberg J, Davey F R, Lowenstein F, Gottlieb A J
Arch Pathol Lab Med. 1978 Jan;102(1):15-8.
A nodular, poorly differentiated lymphocytic lymphoma involving lymph nodes, spleen, and skin is reported in a 60-year-old man. The clinical course of this disorder strongly implied cutaneous involvement as the initial site of disease. Immunologic studies indicated that the neoplastic cells carried surface immunoglobulin (IgMgamma), thus suggesting a B lymphocyte origin for the lymphatic neoplasia.
据报道，一名60岁男性患有结节性、低分化淋巴细胞淋巴瘤，累及淋巴结、脾脏和皮肤。该疾病的临床病程强烈提示皮肤受累为疾病的初始部位。免疫学研究表明，肿瘤细胞携带表面免疫球蛋白（IgMγ），因此提示该淋巴瘤起源于B淋巴细胞。
