人肝移植细针穿刺活检中肝细胞主要组织相容性复合体抗原表达的纵向研究
Longitudinal study of major histocompatibility complex antigen expression on hepatocytes in fine-needle aspiration biopsies from human liver grafts.
作者信息
Vogel W, Wohlfahrter T, Then P, Judmaier G, Knapp W, Margreiter R
机构信息
Department of Medicine, University of Innsbruck, Austria.
出版信息
Transplant Proc. 1988 Aug;20(4):648-9.
PMID:3043827
Abstract
Expression of MHC class II antigens on hepatocytes is part of the natural history of liver grafts. The expression appears to be enhanced by rejection episodes but not during infection and seems to persist on higher levels in chronic rejection and multigraft recipients. Intense expression of class I antigens is a nonspecific feature of the posttransplant situation.
摘要
肝细胞上MHC II类抗原的表达是肝移植自然病程的一部分。这种表达似乎在排斥反应期增强，但在感染期间不会增强，并且在慢性排斥反应和多器官移植受者中似乎持续处于较高水平。I类抗原的强烈表达是移植后情况的一个非特异性特征。
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