Guo Runling, Wang Ying, Wang Yaoyong, Li Yongqiang
Department of Respiratory and Critical Medicine, Fenyang Hospital, Fenyang 032200, Shanxi, China. Corresponding author: Li Yongqiang, Email:
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Oct;30(10):943-945. doi: 10.3760/cma.j.issn.2095-4352.2018.010.007.
To investigate the effect of oxygen therapy with Venturi combined with MR850 heating humidifier on patients without mechanical ventilation after tracheotomy.
Eighty patients (≥ 18 years old) who had undergone tracheotomy and without mechanical ventilation admitted to Fenyang Hospital of Shanxi Province from June 2016 to December 2017 were enrolled, and they were divided into control group and observation group according to random number table method, with 40 patients in each group. The observation group was given Venturi (removed the mask) combined with MR850 device active warm and humid oxygen therapy; the control group was given one-off ordinary flow device and warm and humid exchanger (artificial nose, HME) passive humid oxygen therapy. Body temperature increased by 1 centigrade above basal body temperature, white blood cell count (WBC) increased 2×10/L than the base value, oxygenation index (PaO/FiO) < 300 mmHg (1 mmHg = 0.133 kPa), airway mucosal hemorrhage, pulmonary infection and sputum viscosity were observed in the two groups for 5 days after oxygen therapy.
Among the 80 patients, there were 46 males and 34 females, with an average age of (67.7±12.2) years. Compared with the control group, the incidence of increased body temperature (5.0% vs. 20.0%), the incidence of increased WBC (7.5% vs. 35.0%), the incidence of low PaO/FiO (2.5% vs. 7.5%), the incidence of airway mucosal bleeding (5.0 % vs. 15.0%) and the incidence of pulmonary infection (2.5% vs. 10.0%) were significantly decreased in the observation group (all P < 0.01), and the proportion of sputum viscosity I degree of patients was significantly increased (57.5% vs. 12.5%, P < 0.01).
Venturi combined with MR850 device can effectively control airway temperature and humidity, promote sputum dilution and conducive to drainage, reduce pulmonary infection in adults patients without mechanical ventilation after tracheotomy, thereby reducing postoperative complications of tracheotomy.
探讨文丘里（Venturi）联合MR850加热湿化器给氧对气管切开术后未行机械通气患者的影响。
选取2016年6月至2017年12月在山西省汾阳医院收治的80例气管切开术后未行机械通气的患者（年龄≥18岁），采用随机数字表法分为对照组和观察组，每组40例。观察组给予文丘里（去掉面罩）联合MR850装置主动温湿化给氧；对照组给予一次性普通流量装置及温热湿交换器（人工鼻，HME）被动湿化给氧。观察两组患者氧疗后5天体温较基础体温升高1℃、白细胞计数（WBC）较基础值升高2×10/L、氧合指数（PaO/FiO）<300 mmHg（1 mmHg = 0.133 kPa）、气道黏膜出血、肺部感染及痰液黏稠度情况。
80例患者中，男46例，女34例，平均年龄（67.7±12.2）岁。观察组体温升高发生率（5.0% 比20.0%）、WBC升高发生率（7.5% 比35.0%）、低PaO/FiO发生率（2.5% 比7.5%）、气道黏膜出血发生率（5.0% 比15.0%）及肺部感染发生率（2.5% 比10.0%）均显著低于对照组（均P < 0.01），且患者痰液黏稠度Ⅰ度比例显著高于对照组（57.5% 比12.5%，P < 0.01）。
文丘里联合MR850装置能有效调控气道温度和湿度，促进痰液稀释利于引流，减少气管切开术后未行机械通气成年患者肺部感染，从而降低气管切开术后并发症。
