丙型肝炎病毒中和抗体：疫苗是否仍然可行？
Hepatitis C Virus Neutralizing Antibodies: Is a Vaccine Still Possible?
机构信息
Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY 10065, USA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.
出版信息
Cell Host Microbe. 2018 Nov 14;24(5):620-621. doi: 10.1016/j.chom.2018.10.017.
PMID:30439338
Abstract
Many hurdles have plagued the development of an effective vaccine for hepatitis C virus. In this issue of Cell Host & Microbe, Kinchen et al. (2018) and Flyak et al. (2018) report on the characterization of neutralizing antibodies from individuals that spontaneously cleared infection, providing insights that promise to propel vaccine design forward.
摘要
许多障碍困扰了丙型肝炎病毒有效疫苗的开发。在本期《细胞宿主与微生物》中，Kinchen 等人（2018 年）和 Flyak 等人（2018 年）报告了自发清除感染的个体中中和抗体的特征，这些发现有望推动疫苗设计的发展。
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