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耳鼻咽喉感染继发脑脓肿。386例病例研究。

Cerebral abscesses secondary to otorhinolaryngological infections. A study of 386 cases.

作者信息

Arseni C, Ciurea A V

机构信息

Neurosurgical Clinic, Bucharest.

出版信息

Zentralbl Neurochir. 1988;49(1):22-36.

PMID:3043985
Abstract

A study is presented, of adjacent cerebral abscesses secondary to otorhinolaryngological infections. A total of 386 patients were included. According to frequency, and in relation to the adjacent septic focus the cerebral abscesses were classified as: otogenic--334 cases (86.5%); rhinogenic--47 cases (12.2%); tonsillary--5 cases (1.3%). These abscesses had similar characteristics: they occurred with the highest frequency in the second and the third decade of life, had a higher incidence in males, the otorhinolaryngologic infection had a chronic course with frequent recidives, propagation of the infection from the original focus occurred by continuity or through the venous system, and the clinical picture was marked by symptoms of local and general infection, by meningeal manifestation, and frequently by altered consciousness (somnolence, confusion). Surgical treatment, next to other therapeutic measures (administration of antibiotics, anti-inflammatory drugs, and intensive care) was aimed at improving the vital prognosis. The postoperative mortality was 23.8%. It was also aimed at increasing the functional recovery rate. Neuropsychical sequellae were noted in 54.9% of all cases. After surgery for the cerebral abscess attempts were made at removing the septic focus, preventing any additional risk of cerebral seeding.

摘要

本文介绍了一项关于耳鼻喉科感染继发的相邻脑脓肿的研究。共纳入386例患者。根据发生频率,并结合相邻的感染灶,脑脓肿分为:耳源性——334例(86.5%);鼻源性——47例(12.2%);扁桃体源性——5例(1.3%)。这些脓肿具有相似的特点:发病频率最高的年龄段为第二和第三个十年,男性发病率更高,耳鼻喉科感染病程呈慢性且频繁复发,感染从原发灶通过连续性或静脉系统传播,临床表现以局部和全身感染症状、脑膜表现以及常出现意识改变(嗜睡、意识模糊)为特征。除其他治疗措施(使用抗生素、抗炎药物及重症监护)外,手术治疗旨在改善患者的生存预后。术后死亡率为23.8%。手术还旨在提高功能恢复率。所有病例中有54.9%出现神经精神后遗症。在脑脓肿手术后,尝试清除感染灶,防止脑内播散的任何额外风险。

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