Hoppenbrouwer Xenia L R, Dehkordi Parastoo, Rollinson Aryannah U, Dunsmuir Dustin, Ansermino J Mark, Dumont Guy, Garde Ainara
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:179-182. doi: 10.1109/EMBC.2018.8512216.
Obstructive Sleep Apnea (OSA) is the most common form of sleep-disordered breathing in children. The gold standard to screen for OSA, polysomnography (PSG), requires an overnight stay in the hospital and is resource intensive. The Phone Oximeter is a non-invasive smartphone-based tool to record pulse oximetry. This portable device is able to measure patients over multiple nights while at home, causing less sleep disturbance than PSG and is able to measure night to night variability in sleep. This study analyzed the Screen My Sleep children (SMS) dataset, in which 74 children were monitored over multiple nights with the Phone Oximeter, including one night simultaneously with PSG in the hospital and two nights at home. In this study, we aim to investigate the night to night variability and assess the accuracy of the oxygen desaturation index (ODI) screening for children with significant OSA. In order to assess the performance of the ODI calculation in children, we implemented different ODIs at different desaturation levels and time durations. The variability was studied using a one-way ANOVA, and ODI's performance screening for OSA using the area under the ROC curve (AUC). The implemented ODIs provide similar OSA screening results, using different apnea/hypopnea index (AHI) thresholds, as the ODI recommended for adults by the American academy of sleep medicine (AASM). The ODI provides an AUC of around 0.77, 0.76, 0.94 and 0.97 classifying children with an AHI > 1, AHI > 5 AHI > 10 and AHI > 15, respectively. The SMS dataset shows no significant night to night variability between the two nights at home. However, when comparing with the night at the hospital, both nights at home show a decrease in the lowest SpO value as well as overall SpO signal quality percentage. This study shows that there is variability in SpO signal between at-home versus in hospital settings.
阻塞性睡眠呼吸暂停（OSA）是儿童睡眠呼吸障碍最常见的形式。筛查OSA的金标准是多导睡眠图（PSG），需要在医院过夜，且资源消耗大。手机脉搏血氧仪是一种基于智能手机的非侵入性工具，用于记录脉搏血氧饱和度。这种便携式设备能够在患者在家的多个夜晚进行测量，比PSG造成的睡眠干扰更小，并且能够测量睡眠期间每晚的变化情况。本研究分析了“筛查我的睡眠”儿童（SMS）数据集，其中74名儿童使用手机脉搏血氧仪在多个夜晚进行监测，包括在医院与PSG同时监测的一晚以及在家中的两晚。在本研究中，我们旨在调查每晚的变化情况，并评估用于筛查患有严重OSA儿童的氧饱和度下降指数（ODI）的准确性。为了评估儿童中ODI计算的性能，我们在不同的饱和度下降水平和持续时间实施了不同的ODI。使用单因素方差分析研究变化情况，并使用ROC曲线下面积（AUC）评估ODI对OSA的筛查性能。所实施的ODI使用不同的呼吸暂停/低通气指数（AHI）阈值，提供与美国睡眠医学学会（AASM）为成人推荐的ODI相似的OSA筛查结果。ODI分别对AHI>1、AHI>5、AHI>10和AHI>15的儿童进行分类时，AUC约为0.77、0.76、0.94和0.97。SMS数据集显示在家中的两晚之间没有显著的每晚变化。然而，与在医院的那一晚相比，在家中的两晚最低SpO值以及总体SpO信号质量百分比均有所下降。本研究表明，在家中与医院环境之间SpO信号存在差异。
