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口服阿昔洛韦减少眼部带状疱疹的眼部并发症

Reduction of the ocular complications of herpes zoster ophthalmicus by oral acyclovir.

作者信息

Cobo M

机构信息

Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina 27710.

出版信息

Am J Med. 1988 Aug 29;85(2A):90-3.

PMID:3044100
Abstract

Herpes zoster ophthalmicus (HZO) is a unique form of zoster dermatitis associated with a high rate of ocular complications that tend to be chronic and may cause vision loss. The ocular complications are highly varied, with keratitis and uveitis being more persistent sequellae of HZO. Oral acyclovir treatment of acute HZO reduces the incidence of the more common ocular complications, including keratitis and uveitis. Although patients treated early in the course of this disease experience a greater clinical response, treatment as late as seven days after onset of cutaneous lesions confers a beneficial prophylactic effect with respect to the ocular complications of HZO.

摘要

眼部带状疱疹(HZO)是一种独特的带状疱疹性皮炎形式,伴有高发生率的眼部并发症,这些并发症往往是慢性的,可能导致视力丧失。眼部并发症种类繁多,角膜炎和葡萄膜炎是HZO更持久的后遗症。口服阿昔洛韦治疗急性HZO可降低包括角膜炎和葡萄膜炎在内的较常见眼部并发症的发生率。尽管在该疾病病程早期接受治疗的患者临床反应更大,但在皮肤病变出现后七天内进行治疗对HZO的眼部并发症具有有益的预防作用。

相似文献

1
Reduction of the ocular complications of herpes zoster ophthalmicus by oral acyclovir.口服阿昔洛韦减少眼部带状疱疹的眼部并发症
Am J Med. 1988 Aug 29;85(2A):90-3.
2
Evaluation and management of herpes zoster ophthalmicus.眼部带状疱疹的评估与管理
Am Fam Physician. 2002 Nov 1;66(9):1723-30.
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Comparison of topical and oral acyclovir in early herpes zoster ophthalmicus.局部应用与口服阿昔洛韦治疗早期眼部带状疱疹的比较。
Eye (Lond). 1994;8 ( Pt 6):688-91. doi: 10.1038/eye.1994.170.
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Herpes zoster ophthalmicus following bone marrow transplantation in children.儿童骨髓移植后发生的眼部带状疱疹
Bone Marrow Transplant. 1999 Jun;23(12):1317-20. doi: 10.1038/sj.bmt.1701796.
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[A case of delayed cerebral infarction occurring in puerperium preceded by herpes zoster ophthalmicus in late pregnancy].[1例产后迟发性脑梗死病例,孕期晚期曾患眼带状疱疹]
No To Shinkei. 1999 Jun;51(6):529-33.
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Valaciclovir in herpes zoster ophthalmicus: new indication. An empty clinical assessment file.伐昔洛韦治疗眼部带状疱疹:新适应症。一份空白的临床评估文件。
Prescrire Int. 1999 Jun;8(41):75-6.
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Ocular complications and loss of vision due to herpes zoster ophthalmicus in patients with HIV infection and a comparison with HIV-negative patients.HIV感染患者因眼部带状疱疹所致的眼部并发症及视力丧失,并与HIV阴性患者进行比较。
Int J STD AIDS. 2013 Feb;24(2):106-9. doi: 10.1177/0956462412472303. Epub 2013 May 6.
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Influence of oral acyclovir on ocular complications of herpes zoster ophthalmicus.口服阿昔洛韦对眼部带状疱疹眼部并发症的影响。
Eye (Lond). 1994;8 ( Pt 1):70-4. doi: 10.1038/eye.1994.13.
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[Prevention of ocular complications of herpes zoster ophthalmicus by adequate treatment with acyclovir].[通过阿昔洛韦充分治疗预防眼部带状疱疹的眼部并发症]
Klin Monbl Augenheilkd. 1991 May;198(5):358-60. doi: 10.1055/s-2008-1045980.
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[Oculomotor nerve paralysis with complete ptosis in herpes zoster ophthalmicus: 2 cases].[眼部带状疱疹伴动眼神经麻痹及完全性上睑下垂:2例报告]
Ann Dermatol Venereol. 1997;124(5):401-3.

引用本文的文献

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Pharmacokinetics and safety of multiple-dose valaciclovir in geriatric volunteers with and without concomitant diuretic therapy.多剂量伐昔洛韦在接受和未接受利尿剂治疗的老年志愿者中的药代动力学及安全性
Antimicrob Agents Chemother. 1996 Jan;40(1):80-5. doi: 10.1128/AAC.40.1.80.
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Recognition and treatment of shingles.带状疱疹的识别与治疗。
Drugs. 1994 Oct;48(4):528-48. doi: 10.2165/00003495-199448040-00004.
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Treatment of shingles and post-herpetic neuralgia.带状疱疹及带状疱疹后神经痛的治疗。
BMJ. 1989 Jun 10;298(6687):1537-8. doi: 10.1136/bmj.298.6687.1537.