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主动脉瓣置换前后主动脉瓣狭窄患者的左心室血流动力学

Left Ventricular Blood Flow Dynamics In Aortic Stenosis Before And After Aortic Valve Replacement.

作者信息

Minagawa Tadanori, Saijo Yoshifumi, Oktamuliani Sri, Kurokawa Takafumi, Nakajima Hiroyuki, Hasegawa Kaoru, Matsuoka Takayuki, Shimizu Takuya, Miura Makoto, Ohara Takahiro, Kawamoto Shunsuke

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:3177-3180. doi: 10.1109/EMBC.2018.8512954.

Abstract

Surgical intervention for aortic valve stenosis (AS) has been established; however its diagnosis based on echocardiographic assessment is still limited by aortic valvular velocity, aortic valvular pressure gradients, and color Doppler imaging. Echo-dynamography (EDG) is a method to determine intracardiac flow dynamics, such as two-dimensional blood flow velocity, vortex, and dynamic pressure. These flow dynamics may be influenced by left ventricular (LV) wall motion and the resistance in LV outflow caused by AS. The objective of the present study was to assess the changes and differences in LV vortices and vorticity before and after AS surgery. Five patients who underwent aortic valve replacement surgery for AS and five control patients were included. Besides routine echocardiographic measurement, EDG was applied to determine the two-dimensional blood flow vector and vorticity. The LV vortex flow in the isovolumetric contraction phase had multiple formations in preoperative cases. The clockwise vortex was found in all cases postoperatively; the vortex formation showed no significant difference between postoperative and normal control groups. EDG may serve important information on LV flow dynamics, non-invasively.

摘要

主动脉瓣狭窄(AS)的外科干预已经确立;然而,基于超声心动图评估对其进行诊断仍受主动脉瓣流速、主动脉瓣压力阶差和彩色多普勒成像的限制。回声动力学(EDG)是一种确定心内血流动力学的方法,如二维血流速度、涡流和动压。这些血流动力学可能会受到左心室(LV)壁运动以及AS导致的左心室流出道阻力的影响。本研究的目的是评估AS手术前后左心室涡流和涡度的变化及差异。纳入了5例因AS接受主动脉瓣置换手术的患者和5例对照患者。除了常规超声心动图测量外,还应用EDG来确定二维血流矢量和涡度。术前病例中,等容收缩期左心室涡流有多种形态。术后所有病例均发现顺时针涡流;术后组与正常对照组之间的涡流形成无显著差异。EDG可以无创地提供有关左心室血流动力学的重要信息。

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