Yoshida Y, Kudo Y, Hoshino E, Minagawa Y, Miki N
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4685-4688. doi: 10.1109/EMBC.2018.8513178.
This paper reports successful measurement of even-related potential (ERP) using candle-like dry microneedle electrodes, which can acquire high-quality electroencephalogram (EEG) from hairy parts without any pretreatment. In our previous work, we successfully measured spontaneous EEG activity and its application to assess the stress state of the subjects. ERPs originate from electrophysiological response to stimulus and are one of the most important indices to capture the cognitive and sensory activities. In this work, using the candle-like dry microelectrodes, we demonstrate successful measurement of ERPs elicited by oddball tasks. Two oddball tasks using pure tone stimuli and speech stimuli were assigned to the subjects, where EEG was acquired from the parietal region (Cz in international 10-20 system). Note that no pretreatment, such as removal of hairs and abrasion of the scalp, was applied. As a result, P300 and mismatch negativity (MMN) were successfully measured in the both oddball tasks from the averaged EEG after the stimuli. Based on these results and given the attractive natures of the candle-like dry microneedle electrodes; they do not need any skin treatment and conductive gels and they can measure EEG from the hairy parts, the developed electrodes will accelerate cognitive neuroscience research using ERPs.
本文报道了使用烛状干微针电极成功测量事件相关电位（ERP）的研究，该电极无需任何预处理即可从毛发部位采集高质量脑电图（EEG）。在我们之前的工作中，我们成功测量了自发脑电活动及其在评估受试者应激状态中的应用。ERP源于对刺激的电生理反应，是捕捉认知和感觉活动的最重要指标之一。在这项工作中，我们使用烛状干微电极成功测量了由oddball任务诱发的ERP。给受试者分配了两个使用纯音刺激和语音刺激的oddball任务，在顶叶区域（国际10-20系统中的Cz）采集脑电图。请注意，没有进行任何预处理，如去除毛发和头皮擦伤。结果，在刺激后的平均脑电图中，两个oddball任务均成功测量到了P300和失配负波（MMN）。基于这些结果以及烛状干微针电极的吸引人的特性；它们不需要任何皮肤处理和导电凝胶，并且可以从毛发部位测量脑电图，所开发的电极将加速使用ERP的认知神经科学研究。
