Federal State Scientific Budgetary Institution "Scientific Research Institute of Physiology & Basic Medicine", Novosibirsk, Russia.
Federal State Scientific Budgetary I Institution of Internal and Preventive Medicine, Novosibirsk, Russia.
Transl Psychiatry. 2018 Nov 15;8(1):248. doi: 10.1038/s41398-018-0298-0.
In our study, the frequencies of serotonin transporter gene (5-HTT) polymorphisms and their combinations are compared in the healthy male subjects with antisocial behavior, in general, and in those with its particular forms, as well as in the reference group of MMA fighters. Subjects convicted of unlawful actions were classified into those convicted of violent crimes or non-violent ones. The group of subjects convicted of violent crimes was further subdivided into those convicted of murder, or robbery, or of inflicting grave body injuries. The group of MMA fighters was selected from the subjects without a prior history of antisocial behavior or criminal record in the subjects or their relatives. The frequency of D allele in the groups of convicted subjects and MMA fighters was higher, than in the population sample. Furthermore, the frequencies of D/D and 12/12 genotype combinations were shown to be higher in the group of convicted subjects, especially, in habitual criminals and those convicted of grave crimes or murder. The predisposition of MMA fighters to violent behavior and physical aggressive suppression of an opponent is successfully implemented in their professional career; however, this behavioral pattern appears to represent the controlled aggression.
在我们的研究中，比较了具有反社会行为的健康男性受试者（一般而言）及其特定形式，以及 MMA 格斗运动员对照组中 5-羟色胺转运体基因（5-HTT）多态性及其组合的频率。被判犯有非法行为的受试者被分为犯有暴力犯罪或非暴力犯罪的受试者。犯有暴力犯罪的受试者组进一步细分为犯有谋杀罪、抢劫罪或严重身体伤害罪的受试者。MMA 格斗运动员组是从没有反社会行为或犯罪记录的受试者或其亲属中选择的。与人口样本相比，被判有罪的受试者和 MMA 格斗运动员组的 D 等位基因频率更高。此外，D/D 和 12/12 基因型组合的频率在被判有罪的受试者组中更高，尤其是在惯犯和犯有严重罪行或谋杀罪的人。MMA 格斗运动员将暴力行为和对对手的身体攻击压制倾向成功地应用于他们的职业生涯中；然而，这种行为模式似乎代表了可控的攻击性。
