骨佩吉特病

Paget's disease of bone.

作者信息

Yates A J

出版信息

Baillieres Clin Endocrinol Metab. 1988 Feb;2(1):267-85. doi: 10.1016/s0950-351x(88)80015-6.

Abstract

Paget's disease is a common disorder of bone of presumed viral aetiology which, in a minority of patients, may cause severe symptoms. Both calcitonin and the diphosphonates have specific anti-pagetic effects. Newer diphosphonates, unlike etidronate, do not impair mineralization, and when they become available these will be the drugs of choice. Until that time, both calcitonin and etidronate continue to have a useful place in the management of this disorder.

摘要

佩吉特氏病是一种病因推测为病毒感染的常见骨病，少数患者可能出现严重症状。降钙素和双膦酸盐都有特定的抗佩吉特氏病作用。新型双膦酸盐与依替膦酸盐不同，不会损害骨矿化，一旦上市，将成为首选药物。在此之前，降钙素和依替膦酸盐在这种疾病的治疗中仍有其作用。