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美国12个城市性传播感染筛查强度与抗菌药物耐药性发展之间的关联:一项生态学研究。

Association between intensity of STI screening and development of antimicrobial resistance in in 12 cities in the USA: An ecological study.

作者信息

Kenyon Chris R

机构信息

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, 2000, Belgium.

Department of Medicine, University of Cape Town, Cape Town, South Africa.

出版信息

F1000Res. 2018 Aug 10;7:1237. doi: 10.12688/f1000research.15569.4. eCollection 2018.

Abstract

In this study, we assessed if there was a city-level association between sexually transmitted infection (STI) screening intensity in men who have sex with men and antimicrobial sensitivity in in the United States, 2007 to 2013.  We found positive associations between STI screening intensity and increases in minimum inhibitory concentrations for certain antimicrobials. Not all positive associations were statistically significant and the associations found to be statistically significant varied between the different analyses. Further studies are therefore required to assess if there is a causal relationship between the intensity of STI screening in MSM and gonococcal resistance.

摘要

在本研究中,我们评估了2007年至2013年美国男男性行为者的性传播感染(STI)筛查强度与抗菌药物敏感性之间是否存在城市层面的关联。我们发现STI筛查强度与某些抗菌药物的最低抑菌浓度增加之间存在正相关。并非所有正相关都具有统计学意义,并且在不同分析中发现具有统计学意义的关联也有所不同。因此,需要进一步研究来评估男男性行为者中STI筛查强度与淋球菌耐药性之间是否存在因果关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf8/6289427/d1fc94377cdf/f1000research-7-18434-g0000.jpg

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