药物性肝血管和窦性病变
Drug-induced vascular and sinusoidal lesions of the liver.
作者信息
Valla D, Benhamou J P
出版信息
Baillieres Clin Gastroenterol. 1988 Apr;2(2):481-500. doi: 10.1016/0950-3528(88)90013-9.
PMID:3044472
Abstract
Drugs can induce various vascular and sinusoidal lesions of the liver, in particular hepatic vein thrombosis, veno-occlusive disease, sinusoidal dilatation, peliosis hepatis, hepatoportal sclerosis and angiosarcoma. None of these lesions is specific of drug-induced injury and all of them can be determined by causes other than drugs. However, for one of these lesions, veno-occlusive disease, chemotherapy (and/or irradiation) represents the main aetiology.
摘要
药物可诱发肝脏的各种血管和血窦病变，特别是肝静脉血栓形成、肝小静脉闭塞病、血窦扩张、肝紫癜、肝门静脉硬化和血管肉瘤。这些病变均非药物性损伤所特有，且均可由药物以外的原因引起。然而，对于其中一种病变，即肝小静脉闭塞病，化疗（和/或放疗）是主要病因。
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Drug-induced vascular and sinusoidal lesions of the liver.药物性肝血管和窦性病变
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