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中颅窝入路与经乳突入路手术修复上半规管裂综合征的听力结局的队列研究。

A Cohort Study of Hearing Outcomes Between Middle Fossa Craniotomy and Transmastoid Approach for Surgical Repair of Superior Semicircular Canal Dehiscence Syndrome.

机构信息

Johns Hopkins School of Medicine.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

出版信息

Otol Neurotol. 2018 Dec;39(10):e1160-e1167. doi: 10.1097/MAO.0000000000002040.

DOI:10.1097/MAO.0000000000002040
PMID:30444849
Abstract

OBJECTIVE

To compare postoperative hearing outcomes between transmastoid and middle fossa craniotomy (MFC) approaches for surgical repair of superior semicircular canal dehiscence syndrome (SCDS) in a tertiary referral center.

STUDY DESIGN

Historical cohort study.

SETTING

Tertiary referral center.

PATIENTS

Twelve consecutive SCDS cases who underwent transmastoid plugging of the superior canal; "controls" were 18 audiogram-matched patients who underwent MFC plugging and resurfacing.

MAIN OUTCOME MEASURES

Differences between preoperative, 7-day postoperative, and long-term (>6 wk) postoperative air and bone conduction, speech discrimination scores (SDS), and pure-tone averages (PTA) in TM cases versus MFC controls.

METHODS

MFC controls were selected by matching preoperative bone conduction (BC) pure-tone thresholds from the TM cases within 10-dBs NHL in ≥80% of recorded frequencies. Wilcoxon signed-rank tests were performed to compare primary outcomes between matches, with a Bonferroni corrected p value of 0.004 (n = 13 variables measured at each time period).

RESULTS

No statistically significant differences were found in long-term postoperative air conduction and BC thresholds at any frequency both during the immediate postoperative period as well as at long-term follow-up (p > 0.004). Similarly, there were no differences in long-term SDS or PTA (p > 0.004).

CONCLUSIONS

In this pilot study, there were no long-term significant differences in hearing outcomes between the two repair techniques for SCDS. We recommend continuing with the established practice for recommending surgical repair based on individual patient characteristics and preferences in managing both vestibular and auditory function.

摘要

目的

在一家三级转诊中心比较经乳突和中颅窝入路手术修复上半规管裂综合征(SCDS)的术后听力结果。

研究设计

历史队列研究。

设置

三级转诊中心。

患者

12 例连续 SCDS 患者行上半规管经乳突填塞术;“对照组”为 18 例行中颅窝填塞和表面修复术且听力图匹配的患者。

主要观察指标

TM 组与 MFC 对照组之间术前、术后 7 天和长期(>6 周)术后气导和骨导、言语辨别评分(SDS)和纯音平均(PTA)的差异。

方法

通过在 TM 组中匹配术前骨导(BC)纯音阈值,在≥80%记录频率内将 MFC 对照组的 BC 阈值匹配到 10-dBs NHL 内,对匹配后的主要结局进行 Wilcoxon 符号秩检验,Bonferroni 校正 p 值为 0.004(每个时间点测量 13 个变量)。

结果

在术后即刻和长期随访期间,在任何频率下,长期术后气导和 BC 阈值均无统计学差异(p>0.004)。同样,长期 SDS 或 PTA 也无差异(p>0.004)。

结论

在这项初步研究中,两种修复技术治疗 SCDS 的听力结果在长期内无显著差异。我们建议根据患者的个体特征和对前庭和听觉功能的管理偏好,继续采用既定的手术修复推荐实践。

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Comparison of Transmastoid and Middle Fossa Approaches for Superior Canal Dehiscence Repair: A Multi-institutional Study.经乳突和中颅窝入路修复上半规管裂的比较:一项多机构研究。
Otolaryngol Head Neck Surg. 2019 Jul;161(1):130-136. doi: 10.1177/0194599819835173. Epub 2019 Mar 5.