Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA.
Department of Biology, Washington University in St. Louis, St. Louis, MO 63130, USA.
Cell. 2018 Nov 15;175(5):1182-1184. doi: 10.1016/j.cell.2018.10.051.
Long before pathogenic interactions with eukaryotic cells evolved, bacteria were competing with one another for limited resources. In this issue, Ting et al. (2018) identify previously unappreciated players in the interbacterial arms race that may be the evolutionary ancestors of eukaryotic cell-targeting ADP-ribosyltransferase toxins.
早在与真核细胞发生致病相互作用之前,细菌就已经在为有限的资源而相互竞争。在本期杂志中,Ting 等人(2018 年)鉴定了细菌间军备竞赛中以前未被重视的参与者,它们可能是真核细胞靶向 ADP-ribosyltransferase 毒素的进化祖先。