Miller A, Woods G L
Washington State University College of Veterinary Medicine, Pullman.
Vet Clin North Am Equine Pract. 1988 Aug;4(2):215-20. doi: 10.1016/s0749-0739(17)30637-5.
Reproductive Physiology 1. Twin pregnancies result in high rates of abortion, stillbirth, and neonatal mortality. 2. Twins develop subsequent to multiple ovulations. Multiple ovulations are related to breed, parity, and mare history. Multiple ovulations are most frequently seen in Thoroughbred and Draft mares. Multiple ovulations are more common in barren and perhaps maiden mares than in lactating mares, and they are more common in certain individual mares. 3. Equine embryos are motile in the uterus from the time of first detection (Days 9 to 10) until fixation (Day 16). They are frequently located in the uterine body on Days 9 and 10. 4. Twin embryos have a pattern of motility and fixation similar to that of single embryos, and fixation is more frequently unilateral than bilateral (70 per cent versus 30 per cent, respectively). 5. Mares have an efficient natural embryo-reduction mechanism to eliminate excess (greater than 1) embryos resulting from multiple ovulations. Natural embryo reduction is more successful in unilateral than bilateral twin pregnancies (89 per cent versus 11 per cent successful reduction, respectively). 6. After the establishment of endometrial cups (Days 35 to 40), mares that are aborted will frequently not cycle for several months. Management of Twin Pregnancy 1. Breed all mares regardless of the number of preovulatory follicles. Withholding mares with preovulatory follicles from breeding does not decrease the incidence of twin pregnancy, but it decreases the overall pregnancy rate and results in a loss of breeding time. 2. Check all mares for twins, regardless of the number of detected ovulations.(ABSTRACT TRUNCATED AT 250 WORDS)
生殖生理学
双胎妊娠导致流产、死产和新生儿死亡率的高发生率。
双胎在多次排卵后发育。多次排卵与品种、胎次和母马病史有关。多次排卵最常见于纯种马和挽马。多次排卵在不育母马、可能还有未孕母马中比在泌乳母马中更常见,并且在某些个体母马中更常见。
马胚胎从首次检测到(第9至10天)直至着床(第16天)在子宫内是可移动的。在第9天和第10天它们经常位于子宫体。
双胎胚胎具有与单胎胚胎相似的移动和着床模式,并且着床更常为单侧而非双侧(分别为70%对30%)。
母马有一种有效的自然胚胎消减机制,以消除由多次排卵产生的多余(超过1个)胚胎。自然胚胎消减在单侧双胎妊娠中比双侧双胎妊娠更成功(分别为89%成功消减对11%)。
在子宫内膜杯形成后(第35至40天),流产的母马通常会有几个月不发情。
双胎妊娠的管理
不论排卵前卵泡数量,对所有母马进行配种。不让有排卵前卵泡的母马配种并不会降低双胎妊娠的发生率,但会降低总体妊娠率并导致配种时间的损失。
检查所有母马是否怀有双胎,不论检测到的排卵数量。(摘要截短至250字)