Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, 21, Avenida Catalunya, 46020, Valencia, Spain.
Public Health Laboratory of Valencia, 21, Avenida Catalunya, 46020, Valencia, Spain.
Chemosphere. 2019 Feb;217:558-566. doi: 10.1016/j.chemosphere.2018.11.017. Epub 2018 Nov 5.
In this study, we assessed total mercury levels in hair specimens of 661 children, aged 6 to 11, participating in the BIOVAL programme, a human biomonitoring study carried out by the Health Department of the Regional Government of Valencia (Spain). The reference value (95th percentile) determined for this population, within this programme, was 3.25 μg g. Hg concentrations ranged between 0.03 μg g and 8.71 μg g, with a geometric mean of 0.79 (CI 95%: 0.73-0.85) μg g. This mean value was five times higher than the average levels found in children of 17 other European countries (0.145 μg g). About 13% of children had hair mercury levels above the FAO/WHO JECFA guideline of 2.3 μg g and 18% of children had levels above the EFSA health-based guidance value of 1.9 μg. Multiple regression analysis revealed that fish consumption, mother's country of birth (Spain or abroad) and the employment situation of parents were the main predictors of mercury in hair.
在这项研究中,我们评估了 661 名 6 至 11 岁儿童的头发样本中的总汞含量,这些儿童参与了 BIOVAL 计划,这是瓦伦西亚地区政府卫生部门进行的一项人体生物监测研究(西班牙)。在该计划中,为该人群确定的参考值(95% 百分位)为 3.25μg/g。Hg 浓度范围在 0.03μg/g 和 8.71μg/g 之间,几何平均值为 0.79(95%CI:0.73-0.85)μg g。这个平均值是其他 17 个欧洲国家儿童平均水平(0.145μg/g)的五倍。约 13%的儿童头发中的汞含量高于粮农组织/世卫组织 JECFA 的 2.3μg/g 指导值,18%的儿童头发中的汞含量高于 EFSA 的基于健康的指导值 1.9μg/g。多元回归分析表明,鱼类消费、母亲的出生国(西班牙或国外)和父母的就业状况是头发中汞的主要预测因素。