a Department of Gastroenterology and Hepatology , Kasturba Medical College, Manipal Academy of Higher Education (MAHE) , Manipal , India.
b Department of Pharmacotherapy , UNTS College of Pharmacy, University of North Texas Health Science Center , Fort Worth , TX , USA.
Postgrad Med. 2019 Jan;131(1):60-67. doi: 10.1080/00325481.2019.1549458. Epub 2018 Nov 25.
Patient education is important in irritable bowel syndrome (IBS), but its effects on outcomes have not been studied extensively.
Patients were enrolled and prospectively divided into an interventional and usual care group. Both received standard of care, but the former additionally received video-assisted patient education. Self-administered questionnaires IBS-quality of life (QOL), Beck Anxiety-Depression Inventory II (BAI, BDI), and Hospital Anxiety and Depression Scale (HADS) were administered at baseline, 3 months, and 6 months. Compliance was defined as drug intake of >80% of the prescribed dose. COI included prospective, prevalence-based, societal perspective.
Of the 107 patients included, 84 [78.5%; male = 66 (78.57%); median age = 44 (range 20-77 years)] completed the follow up. While the median (inter-quartile range; IQR) QOL scores decreased significantly in both the groups (p < 0.001 for either group), the final scores were significantly better in the interventional group [49 (44-52.5) versus 80 (76-103), respectively; p < 0.005]. There was a significant improvement in the BDI; p < 0.001]. However, the rest did not achieve statistical significance. At 6 months, total median (IQR) semi-annual cost per patient was INR 14,639 (8253-17,909) [US $240 (135-294].
Video-assisted patient education should be a part of the treatment of IBS since it improves the QOL and depression scores.
患者教育在肠易激综合征(IBS)中很重要,但它对结局的影响尚未得到广泛研究。
患者被纳入并前瞻性地分为干预组和常规护理组。两组均接受标准治疗,但前者另外接受视频辅助的患者教育。在基线、3 个月和 6 个月时,患者自行填写肠易激综合征生活质量(IBS-QOL)问卷、贝克焦虑抑郁量表 II(BAI、BDI)和医院焦虑抑郁量表(HADS)。依从性定义为药物摄入量超过规定剂量的 80%。利益冲突包括前瞻性、基于流行率的、社会角度。
在 107 例纳入的患者中,84 例[78.5%;男性=66 例(78.57%);中位年龄=44 岁(范围 20-77 岁)]完成了随访。虽然两组的 QOL 评分中位数(四分位距;IQR)均显著下降(两组均 p < 0.001),但干预组的最终评分明显更好[49(44-52.5)比 80(76-103),分别;p < 0.005]。BDI 显著改善;p < 0.001]。然而,其余的没有达到统计学意义。在 6 个月时,每位患者的总半年中位数(IQR)费用为 14639 卢比(8253-17909)[240 美元(135-294 美元]。
视频辅助的患者教育应该成为 IBS 治疗的一部分,因为它可以提高生活质量和抑郁评分。