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衰老和共病如何影响房颤患者缺血性卒中的风险。

How do aging and comorbidities impact risk of ischemic stroke in patients with atrial fibrillation.

机构信息

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, and Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan.

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, and Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan.

出版信息

Trends Cardiovasc Med. 2019 Oct;29(7):386-391. doi: 10.1016/j.tcm.2018.11.003. Epub 2018 Nov 6.

DOI:10.1016/j.tcm.2018.11.003
PMID:30446380
Abstract

Stroke is a notorious complication in patients with atrial fibrillation (AF) and risk stratification is pivotal for stroke prevention strategy. The risk of AF-related stroke is a mixture of complex interaction between increasing age and important comorbidities. Therefore, this article aims to provide a comprehensive review on these important risk factors of stroke in AF patients, mainly focusing on the component of CHADS-VASc score, as well as some other potential risk factors.

摘要

中风是房颤(AF)患者的一种严重并发症,风险分层对于预防中风策略至关重要。AF 相关中风的风险是年龄增长和重要合并症之间复杂相互作用的混合体。因此,本文旨在全面综述 AF 患者中风的这些重要危险因素,主要集中在 CHADS-VASc 评分的组成部分以及一些其他潜在的危险因素。

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Front Aging Neurosci. 2022 May 9;14:863489. doi: 10.3389/fnagi.2022.863489. eCollection 2022.
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CXCR4 and TYROBP mediate the development of atrial fibrillation via inflammation.CXCR4 和 TYROBP 通过炎症介导心房颤动的发生。
J Cell Mol Med. 2022 Jun;26(12):3557-3567. doi: 10.1111/jcmm.17405. Epub 2022 May 23.
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Novel model-based point scoring system for predicting stroke risk in atrial fibrillation patients: Results from a nationwide cohort study with validation.
基于新型模型的房颤患者卒中风险评分系统:一项全国性队列研究及验证结果
Int J Cardiol Heart Vasc. 2021 Apr 28;34:100787. doi: 10.1016/j.ijcha.2021.100787. eCollection 2021 Jun.