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采用冷冻胶囊进行粪便微生物群移植治疗难治性急性肠道移植物抗宿主病。

Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease.

机构信息

Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.

Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan; and.

出版信息

Blood Adv. 2018 Nov 27;2(22):3097-3101. doi: 10.1182/bloodadvances.2018024968.

DOI:10.1182/bloodadvances.2018024968
PMID:30446486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6258918/
Abstract

Bacterial diversity was restored after FMT with oral frozen capsules, with improvement of diarrhea. Oral FMT for steroid-refractory acute gGVHD is feasible and could be effective.

摘要

粪便微生物移植（FMT）采用口服冷冻胶囊后，细菌多样性得到恢复，腹泻症状得到改善。口服 FMT 治疗类固醇难治性急性移植物抗宿主病是可行的，并且可能有效。

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Effect of Oral Capsule- vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial.口服胶囊与结肠镜检查递送粪便微生物群移植对复发性艰难梭菌感染的影响：一项随机临床试验
JAMA. 2017 Nov 28;318(20):1985-1993. doi: 10.1001/jama.2017.17077.
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Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection.粪便过滤移植治疗艰难梭菌感染的疗效。
Gastroenterology. 2017 Mar;152(4):799-811.e7. doi: 10.1053/j.gastro.2016.11.010. Epub 2016 Nov 17.
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