入住有或没有专门烧伤中心的医院的烧伤患者的损伤流行病学、治疗（费用）及结局（Burn-Pro）：一项多中心前瞻性观察性研究方案
Epidemiology of injuries, treatment (costs) and outcome in burn patients admitted to a hospital with or without dedicated burn centre (Burn-Pro): protocol for a multicentre prospective observational study.
作者信息
Van Lieshout Esther Mm, Van Yperen Daan T, Van Baar Margriet E, Polinder Suzanne, Boersma Doeke, Cardon Anne Ymvp, De Rijcke Piet Ar, Guijt Marc, Klem Taco Mal, Lansink Koen Ww, Ringburg Akkie N, Staarink Maarten, Van de Schoot Leon, Van der Veen Alexander H, Van Eijck Floortje C, Van Eerten Percy V, Vegt Paul A, Vos Dagmar I, Waleboer Marco, Verhofstad Michael Hj, Van der Vlies Cornelis H
机构信息
Trauma Research Unit Department of Surgery, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Burn Center, Maasstad Hospital, Rotterdam, Zuid-Holland, The Netherlands.
出版信息
BMJ Open. 2018 Nov 15;8(11):e023709. doi: 10.1136/bmjopen-2018-023709.
INTRODUCTION
The Emergency Management of Severe Burns (EMSB) referral criteria have been implemented for optimal triaging of burn patients. Admission to a burn centre is indicated for patients with severe burns or with specific characteristics like older age or comorbidities. Patients not meeting these criteria can also be treated in a hospital without burn centre. Limited information is available about the organisation of care and referral of these patients. The aims of this study are to determine the burn injury characteristics, treatment (costs), quality of life and scar quality of burn patients admitted to a hospital without dedicated burn centre. These data will subsequently be compared with data from patients with<10% total bodysurface area (TBSA) burned who are admitted (or secondarily referred) to a burn centre. If admissions were in agreement with the EMSB, referral criteria will also be determined.
METHODS AND ANALYSIS
In this multicentre, prospective, observational study (cohort study), the following two groups of patients will be followed: 1) all patients (no age limit) admitted with burn-related injuries to a hospital without a dedicated burn centre in the Southwest Netherlands or Brabant Trauma Region and 2) all patients (no age limit) with<10% TBSA burned who are primarily admitted (or secondarily referred) to the burn centre of Maasstad Hospital. Data on the burn injury characteristics (primary outcome), EMSB compliance, treatment, treatment costs and outcome will be collected from the patients' medical files. At 3 weeks and at 3, 6 and 12 months after trauma, patients will be asked to complete the quality of life questionnaire (EuroQoL-5D), and the patient-reported part of the Patient and Observer Scar Assessment Scale (POSAS). At those time visits, the coordinating investigator or research assistant will complete the observer-reported part of the POSAS.
ETHICS AND DISSEMINATION
This study has been exempted by the medical research ethics committee Erasmus MC (Rotterdam, The Netherlands). Each participant will provide written consent to participate and remain encoded during the study. The results of the study are planned to be published in an international, peer-reviewed journal.
TRIAL REGISTRATION NUMBER
NTR6565.
引言
已实施严重烧伤应急管理（EMSB）转诊标准，以实现烧伤患者的最佳分诊。严重烧伤患者或具有年龄较大或合并症等特定特征的患者需入住烧伤中心。不符合这些标准的患者也可在没有烧伤中心的医院接受治疗。关于这些患者的护理组织和转诊的信息有限。本研究的目的是确定入住没有专门烧伤中心的医院的烧伤患者的烧伤损伤特征、治疗（费用）、生活质量和瘢痕质量。随后将这些数据与烧伤总面积小于10%且入住（或二次转诊）烧伤中心的患者的数据进行比较。如果入院符合EMSB标准，还将确定转诊标准。
方法与分析
在这项多中心、前瞻性观察性研究（队列研究）中，将对以下两组患者进行随访：1）所有因烧伤相关损伤入住荷兰西南部或布拉班特创伤地区没有专门烧伤中心的医院的患者（无年龄限制），以及2）所有烧伤总面积小于10%且首次入住（或二次转诊）马斯斯塔德医院烧伤中心的患者（无年龄限制）。将从患者的医疗档案中收集烧伤损伤特征（主要结局）、EMSB依从性、治疗、治疗费用和结局的数据。在创伤后3周以及3、6和12个月时，将要求患者完成生活质量问卷（欧洲五维健康量表）以及患者报告的患者和观察者瘢痕评估量表（POSAS）部分。在这些访视时，协调研究者或研究助理将完成POSAS的观察者报告部分。
伦理与传播
本研究已获得伊拉斯谟医学中心（荷兰鹿特丹）医学研究伦理委员会的豁免。每位参与者将提供书面知情同意书以参与研究，并在研究期间保持编码状态。研究结果计划发表在国际同行评审期刊上。
试验注册号
NTR6565。
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