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胸痛伴肌钙蛋白水平升高;并不总是心脏病学问题。

Chest pain with increased troponin level; not always a cardiology issue.

作者信息

Papadatos Stamatis S, Karakatsanis Stamatis J, Deligiannis George, Gatsa Eleni

机构信息

3Department of Internal Medicine, National and Kapodistrian University of Athens School of Medicine, Sotiria General Hospital, Athens, Greece.

Hematology Unit, 3rd Department of Internal Medicine, National and Kapodistrian University of Athens School of Medicine, Sotiria General Hospital, Athens, Greece.

出版信息

Rom J Intern Med. 2019 Jun 1;57(2):201-204. doi: 10.2478/rjim-2018-0037.

Abstract

Thrombotic Thrombocytopenic Purpura (TTP) is a thrombotic microangiopathy syndrome resulting from decrease or absence of "a disintegrin and metalloproteinase with a thrombospondin type 1 motif member 13" (ADAMTS13). TTP has been characterized by the classical pentad of thrombocytopenia, hemolysis, fever, renal injury and neurological deficits, yet the patient may present with any atypical symptom related to microthrombi formation in the microcirculation. Here we present a rare case of a young patient with retrosternal chest pain and myocardial injury as the first manifestation of TTP.

摘要

血栓性血小板减少性紫癜(TTP)是一种由“具有Ⅰ型血小板反应蛋白基序的解聚素和金属蛋白酶13”(ADAMTS13)减少或缺乏引起的血栓性微血管病综合征。TTP的典型特征为血小板减少、溶血、发热、肾损伤和神经功能缺损这一经典五联征,但患者可能表现出与微循环中微血栓形成相关的任何非典型症状。在此,我们报告一例罕见的年轻患者,其以胸骨后胸痛和心肌损伤作为TTP的首发表现。

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