Shah Ravi, Zanarini Mary C
Laboratory for the Study of Adult Development, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA.
Laboratory for the Study of Adult Development, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA; Department of Psychiatry, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA.
Psychiatr Clin North Am. 2018 Dec;41(4):583-593. doi: 10.1016/j.psc.2018.07.009. Epub 2018 Oct 16.
Patients with borderline personality disorder have high rates of comorbid mood, anxiety, substance use, and eating disorders. The longitudinal studies conducted on borderline patients over 10 years of prospective follow-up suggest that patients with borderline personality disorder experienced declining rates of Axis I disorders over time, but the rates of these disorders remained high compared with those with other personality disorders. In addition, patients whose borderline personality disorder remitted over time experienced a substantial decline in all comorbid Axis I disorders, but those whose borderline personality disorder did not remit over time, reported stable rates of comorbid disorders.
边缘型人格障碍患者共病情绪障碍、焦虑障碍、物质使用障碍和进食障碍的发生率很高。对边缘型人格障碍患者进行的长达10年的前瞻性随访纵向研究表明，随着时间的推移，边缘型人格障碍患者的轴I障碍发生率呈下降趋势，但与其他人格障碍患者相比，这些障碍的发生率仍然很高。此外，随着时间的推移边缘型人格障碍症状缓解的患者，其所有共病的轴I障碍都有大幅下降，但那些边缘型人格障碍症状未随时间缓解的患者，报告的共病障碍发生率保持稳定。
