Department of Cardiology, Marshfield Clinic Health Care System, Marshfield, WI, United States.
Huntington Medical Research Institute, Pasadena, CA 91105, United States.
Trends Cardiovasc Med. 2019 Oct;29(7):403-407. doi: 10.1016/j.tcm.2018.11.004. Epub 2018 Nov 10.
More than four decades ago, the United States Surgeon General issued a warning regarding the medical problems of marijuana smoking, including cardiac toxicity. Since then, many reports have described atrial fibrillation, ventricular tachycardia, acute coronary syndromes, and cardiac arrest temporally related to marijuana use. The subjects were quite young, with no significant cardiovascular risk factors, with the only obvious trigger being marijuana use. Despite these strong signals, the drug is now legalized for recreational use in many states. We believe the time has come to conduct definitive studies about the safety of marijuana before this trend moves to the rest of the nation.
四十多年前，美国外科医生总署就大麻吸烟的医学问题发出警告，包括心脏毒性。从那时起，许多报告描述了与大麻使用相关的心房颤动、室性心动过速、急性冠状动脉综合征和心脏骤停。这些患者年龄相当年轻，没有明显的心血管危险因素，唯一明显的诱因是大麻使用。尽管有这些强烈的信号，但该药物现在在许多州已合法化供娱乐使用。我们认为，在这一趋势蔓延到全国其他地区之前，现在是时候对大麻的安全性进行明确的研究了。
