Dissanayake P V, Muthukumarana T G W, Aslam W A M, Chaminda S A A, Munasinghe T S, Kularatne S A M
Department of Pediatrics, Faculty of Medicine, University of Peradeniya, 20400, Sri Lanka.
Teaching Hospital, Peradeniya, 20400, Sri Lanka.
Toxicon. 2019 Jan;157:77-79. doi: 10.1016/j.toxicon.2018.11.299. Epub 2018 Nov 16.
Overt myoglobinuria associated with myotoxicity is a classic feature of sea snake envenomation. Russell's viper bites usually result in coagulopathy, neurotoxicity and nephrotoxicity but rarely myotoxicity has been reported, especially in the Sri Lankan variety (Daboia russelii). All those studies have demonstrated mild degree myotoxicity with microscopic level myoglobinuria. We report what is probably the first case of gross myoglobinuria in a child following a Russell's viper bite with biochemical evidence of significant myotoxicity well beyond the levels that have been previously reported.
与肌毒性相关的显性肌红蛋白尿是海蛇咬伤的典型特征。罗素蝰蛇咬伤通常会导致凝血病、神经毒性和肾毒性，但很少有肌毒性的报道，尤其是在斯里兰卡品种（罗素蝰蛇）中。所有这些研究都表明存在轻度肌毒性以及镜下血尿。我们报告了可能是首例被罗素蝰蛇咬伤的儿童出现肉眼可见的肌红蛋白尿的病例，并有生化证据表明存在明显的肌毒性，其程度远超先前报道的水平。
