高频眶上神经刺激治疗创伤后神经痛的新型微创无线设备:病例报告。
High-Frequency Supraorbital Nerve Stimulation With a Novel Wireless Minimally Invasive Device for Post-Traumatic Neuralgia: A Case Report.
机构信息
AZ Nikolaas Hospital, Sint-Niklaas, Belgium.
StimRelieve LLC, Pompano Beach, Florida, U.S.A.
出版信息
Pain Pract. 2019 Apr;19(4):435-439. doi: 10.1111/papr.12747. Epub 2019 Feb 6.
BACKGROUND
Post-traumatic neuropathic pain in the head and face is a condition that is often refractory to medical management. Peripheral nerve stimulation (PNS) can be an effective treatment. Successful implantation of a novel minimally invasive wireless device is reported here.
OBJECTIVE
To assess analgesic effects of a minimally invasive wireless PNS device in the treatment of post-traumatic supraorbital neuralgia (SON).
CASE SUMMARY
The patient presented with SON following multiple post-traumatic cranioplasty surgeries, which were complicated by infections. Medical and interventional management failed, and the patient reported a numeric rating scale (NRS) pain score of 8 out of 10. Two octopolar implantable neural stimulators (INSs) (StimRelieve LLC, Pompano Beach, FL, U.S.A.) were implanted with a minimally invasive, percutaneous technique to stimulate the supraorbital nerves. Stimulation parameters were set at a frequency of 10 kHz and a pulse width of 30 microseconds.
RESULTS
At 12- and 24-month follow-up evaluations, the patient's NRS score was only 2 out of 10, and the patient occasionally required 1 g of paracetamol to control the pain. Stimulation was reported to be paresthesia free. There were no adverse events related to the procedure or the treatment until today.
CONCLUSIONS
High-frequency stimulation with an external pulse generator and minimally invasive, percutaneous, and bilateral placement of 2 passive INSs on the supraorbital nerves resulted in a significant pain relief in this patient with post-traumatic SON. The device was safe and effective, and the cosmesis was satisfactory.
背景
头面部创伤后神经病理性疼痛是一种通常对药物治疗反应不佳的疾病。周围神经刺激(PNS)可能是一种有效的治疗方法。这里报告了一种新型微创无线设备成功植入的案例。
目的
评估微创无线 PNS 设备在治疗创伤后眶上神经痛(SON)中的镇痛效果。
病例总结
患者因多次创伤性颅骨修补术后感染而出现 SON。药物和介入治疗均失败,患者自述数字评分量表(NRS)疼痛评分为 10 分中的 8 分。使用微创经皮技术植入了两个八极可植入神经刺激器(INS)(StimRelieve LLC,美国佛罗里达州庞帕诺海滩),以刺激眶上神经。刺激参数设置为频率 10 kHz,脉冲宽度 30 微秒。
结果
在 12 个月和 24 个月的随访评估时,患者的 NRS 评分为 2 分,偶尔需要 1 克对乙酰氨基酚来控制疼痛。报告称刺激无感觉异常。直到今天,没有与手术或治疗相关的不良事件。
结论
高频刺激外加外部脉冲发生器,以及微创、经皮、双侧将 2 个无源 INS 放置在眶上神经上,使创伤后 SON 患者的疼痛显著缓解。该设备安全有效,美容效果令人满意。