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枕神经刺激治疗难治性枕神经痛:病例系列

Occipital Nerve Stimulation for the Treatment of Refractory Occipital Neuralgia: A Case Series.

作者信息

Keifer Orion P, Diaz Ashley, Campbell Melissa, Bezchlibnyk Yarema B, Boulis Nicholas M

机构信息

Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA.

Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

World Neurosurg. 2017 Sep;105:599-604. doi: 10.1016/j.wneu.2017.06.064. Epub 2017 Jun 17.

Abstract

BACKGROUND

Occipital neuralgia is a chronic pain syndrome characterized by sharp, shooting pains in the distribution of the occipital nerves. Although relatively rare, it associated with extremely debilitating symptoms that drastically affect a patient's quality of life. Furthermore, it is extremely difficult to treat as the symptoms are refractory to traditional treatments, including pharmacologic and procedural interventions. A few previous case studies have established the use of a neurostimulation of the occipital nerves to treat occipital neuralgia.

OBJECTIVE

The following expands on that literature by retrospectively reviewing the results of occipital nerve stimulation in a relatively large patient cohort (29 patients).

METHODS

A retrospective review of 29 patients undergoing occipital nerve stimulation for occipital neuralgia from 2012 to 2017 at a single institution with a single neurosurgeon.

RESULTS

Of those 29 patients, 5 were repair or replacement of previous systems, 4 did not have benefit from trial stimulation, and 20 saw benefit to their trial stage of stimulation and went on to full implantation. Of those 20 patients, even with a history of failed procedures and pharmacological therapies, there was an overall success rate of 85%. The average preoperative 10-point pain score dropped from 7.4 ± 1.7 to a postoperative score of 2.9 ± 1.7. However, as with any peripheral nerve stimulation procedure, there were complications (4 patients), including infection, hardware erosion, loss of effect, and lead migration, which required revision or system removal.

CONCLUSION

Despite complications, the results suggest, overall, that occipital nerve stimulation is a safe and effective procedure for refractory occipital neuralgia and should be in the neurosurgical repertoire for occipital neuralgia treatment.

摘要

背景

枕神经痛是一种慢性疼痛综合征,其特征为枕神经分布区域出现尖锐的、刺痛性疼痛。尽管相对罕见,但它会引发极其使人衰弱的症状,严重影响患者的生活质量。此外,由于这些症状对包括药物和手术干预在内的传统治疗方法具有难治性,因此极难治疗。此前已有一些病例研究证实了使用枕神经刺激来治疗枕神经痛。

目的

通过回顾性分析一个相对较大患者队列(29例患者)的枕神经刺激结果,对该文献进行拓展。

方法

对2012年至2017年在一家机构由一位神经外科医生为29例枕神经痛患者进行枕神经刺激的情况进行回顾性分析。

结果

在这29例患者中,5例是对先前系统进行修复或更换,4例未从试验性刺激中获益,20例在试验性刺激阶段获益并继续进行完全植入。在这20例患者中,即使有手术和药物治疗失败的病史,总体成功率仍为85%。术前平均10分制疼痛评分从7.4±1.7降至术后的2.9±1.7。然而,与任何周围神经刺激手术一样,出现了并发症(4例患者),包括感染、硬件侵蚀、效果丧失和导线移位,这需要进行翻修或移除系统。

结论

尽管有并发症,但总体结果表明,枕神经刺激对于难治性枕神经痛是一种安全有效的手术,应纳入枕神经痛治疗的神经外科手术方案中。

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