Department of Medicine, Cardiology Division, Rush University Medical Center, 1653 West Congress Parkway, Chicago, IL 60612, USA.
Department of Medicine, Cardiology Division, Hoag Memorial Hospital, University of California, Irvine, 520 Superior Avenue, Newport Beach, CA 92663, USA.
Heart Fail Clin. 2019 Jan;15(1):55-64. doi: 10.1016/j.hfc.2018.08.006. Epub 2018 Oct 24.
Atrial fibrillation often occurs as a cause or consequence of heart failure. Clinical outcomes are worse when atrial fibrillation and heart failure coexist. There are important sex-related differences in the incidence, prevalence, pathophysiology, treatment, and outcomes of these patients. Women with heart failure are at greater risk of developing atrial fibrillation than men, and more women with atrial fibrillation develop heart failure. More women die of atrial fibrillation-related strokes. Despite significant morbidity and mortality, current treatments for women are inadequate. This review explores sex differences in atrial fibrillation and heart failure, emphasizing risk stratification and treatments to improve clinical outcomes.
心房颤动常作为心力衰竭的病因或后果出现。当心房颤动和心力衰竭并存时,临床结局更差。这些患者的发病率、患病率、病理生理学、治疗和结局存在重要的性别相关差异。心力衰竭女性发生心房颤动的风险高于男性,而更多的心房颤动女性发展为心力衰竭。更多女性死于与心房颤动相关的卒中。尽管发病率和死亡率显著,但目前女性的治疗方法仍不充分。本综述探讨了心房颤动和心力衰竭中的性别差异,强调了风险分层和治疗措施以改善临床结局。