Afzali Payam, Ward Brent Benson
Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI, USA.
Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI, USA.
Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):69-84. doi: 10.1016/j.coms.2018.09.004.
Nodal metastasis is the single most prognostic determinant in patients with oral squamous cell carcinoma (OSCC). Since its inception more than a century ago, the management of the neck has led to decreased surgical morbidity, with continued preservation of oncologic safety for OSCC. Nodal metastasis is the single most prognostic determinant in patients with OSCC. The decision for the extent of the neck dissection is tailored to tumor-specific characteristics, which dictate the probability and extent of nodal metastasis, including tumor size, location, histopathologic characteristics, and the presence or absence of clinical nodal disease. These factors are tools to aid diagnosticians in their decision making for individual patients.
淋巴结转移是口腔鳞状细胞癌（OSCC）患者最重要的预后决定因素。自一个多世纪前首次出现以来，颈部的治疗方法已降低了手术发病率，同时持续保障了OSCC患者的肿瘤学安全性。淋巴结转移是OSCC患者最重要的预后决定因素。颈部清扫范围的决策是根据肿瘤的特定特征量身定制的，这些特征决定了淋巴结转移的可能性和范围，包括肿瘤大小、位置、组织病理学特征以及临床淋巴结疾病的有无。这些因素是帮助诊断医生为个体患者做出决策的工具。
