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老年患者处理困难的钙化冠状动脉病变时经桡动脉旋磨术与经股动脉途径的比较——单中心经验

Advantages of Transradial Rotational Atherectomy versus Transfemoral Approach in Elderly Patients with Hard-Handling Calcified Coronary Lesions - A Single Center Experience.

作者信息

You Wei, Wu Xiang-Qi, Ye Fei, Chen Shao-Liang

机构信息

Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

出版信息

Acta Cardiol Sin. 2018 Nov;34(6):464-471. doi: 10.6515/ACS.201811_34(6).20180427A.

DOI:10.6515/ACS.201811_34(6).20180427A
PMID:30449986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6236566/
Abstract

BACKGROUND

Balloons cannot pass through severely calcified coronary lesion (SCCL), and sometimes they cannot be opened at a high pressure even if they can pass through the lesion. There are limited data on rotational atherectomy (RA) via transradial access (TRA) in this setting. The aim of this study was to evaluate in-hospital and 1-year outcomes in elderly patients with SCCL who underwent RA via TRA.

METHODS

Eighty-six consecutive elderly patients with de novo SCCL who underwent RA were enrolled and divided into TRA (n = 45) and transfemoral access (TFA, n = 41) groups in this retrospective analysis from 2008 to 2013. Baseline characteristics and in-hospital and 1-year endpoints were compared between both groups.

RESULTS

Compared to TFA, 6Fr guide catheters were used significantly more in the radial approach (p < 0.001). In the TRA group, the rate of burr size (1.25 mm) was higher and the mean burr size was smaller (p = 0.021) than that in the TFA group. Vascular access site complications, bed rest time and hospital stay were significantly lower in the TRA group compared with the TFA group (p = 0.029, < 0.001, < 0.001, respectively). However, there was no significant difference in major adverse cardiac events during hospitalization and after 1 year follow-up between both groups (p = 0.338, 1.000, respectively).

CONCLUSIONS

TRA is a useful alternative to TFA in elderly patient with SCCL. The advantages of TRA over TFA include reduced time of bed rest and hospital stay and vascular complications at the puncture site.

摘要

背景

球囊无法通过严重钙化的冠状动脉病变(SCCL),有时即使球囊能够通过病变,也无法在高压下打开病变。在这种情况下,经桡动脉途径(TRA)进行旋磨术(RA)的数据有限。本研究的目的是评估经TRA行RA的老年SCCL患者的院内及1年预后。

方法

本回顾性分析纳入了86例连续接受RA的初发SCCL老年患者,在2008年至2013年期间将其分为TRA组(n = 45)和经股动脉途径(TFA,n = 41)组。比较两组的基线特征、院内及1年终点。

结果

与TFA相比,桡动脉途径显著更多地使用6Fr引导导管(p < 0.001)。在TRA组中,1.25mm的磨头尺寸使用率更高,且平均磨头尺寸小于TFA组(p = 0.021)。与TFA组相比,TRA组的血管入路部位并发症、卧床时间和住院时间显著更低(分别为p = 0.029、< 0.001、< 0.001)。然而,两组在住院期间及1年随访后的主要不良心脏事件方面无显著差异(分别为p = 0.338、1.000)。

结论

对于老年SCCL患者,TRA是TFA的一种有用替代方法。TRA相对于TFA的优势包括减少卧床时间和住院时间以及穿刺部位的血管并发症。

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Safety and efficacy of transradial coronary angiography and intervention in patients older than 80 years: from the Korean Transradial Intervention Prospective Registry.80岁以上患者经桡动脉冠状动脉造影及介入治疗的安全性和有效性:来自韩国经桡动脉介入治疗前瞻性注册研究
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Successful Retrieval of an Entrapped Rotablator Burr by Using a Guideliner Guiding Catheter and a Snare.使用导丝引导导管和圈套器成功取出嵌顿的旋磨钻。
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Comparison of Clinical Outcomes in Patients Undergoing Coronary Intervention with Drug-Eluting Stents or Bare-Metal Stents: A Nationwide Population Study.药物洗脱支架与裸金属支架冠状动脉介入治疗患者临床结局的比较:一项全国性人群研究。
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Transradial versus transfemoral rotablation for heavily calcified coronary lesions in contemporary drug-eluting stent era.当代药物洗脱支架时代经桡动脉与经股动脉旋磨术治疗严重钙化冠状动脉病变的比较
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Rotational atherectomy through the radial artery is associated with similar procedural success when compared with the transfemoral route.与经股动脉途径相比,经桡动脉进行旋磨术的手术成功率相似。
Coron Artery Dis. 2015 May;26(3):254-8. doi: 10.1097/MCA.0000000000000198.
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Current status of rotational atherectomy.旋磨术的现状。
JACC Cardiovasc Interv. 2014 Apr;7(4):345-53. doi: 10.1016/j.jcin.2013.12.196. Epub 2014 Mar 13.
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Hellenic J Cardiol. 2011 Sep-Oct;52(5):399-406.
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