You Wei, Wu Xiang-Qi, Ye Fei, Chen Shao-Liang
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Acta Cardiol Sin. 2018 Nov;34(6):464-471. doi: 10.6515/ACS.201811_34(6).20180427A.
Balloons cannot pass through severely calcified coronary lesion (SCCL), and sometimes they cannot be opened at a high pressure even if they can pass through the lesion. There are limited data on rotational atherectomy (RA) via transradial access (TRA) in this setting. The aim of this study was to evaluate in-hospital and 1-year outcomes in elderly patients with SCCL who underwent RA via TRA.
Eighty-six consecutive elderly patients with de novo SCCL who underwent RA were enrolled and divided into TRA (n = 45) and transfemoral access (TFA, n = 41) groups in this retrospective analysis from 2008 to 2013. Baseline characteristics and in-hospital and 1-year endpoints were compared between both groups.
Compared to TFA, 6Fr guide catheters were used significantly more in the radial approach (p < 0.001). In the TRA group, the rate of burr size (1.25 mm) was higher and the mean burr size was smaller (p = 0.021) than that in the TFA group. Vascular access site complications, bed rest time and hospital stay were significantly lower in the TRA group compared with the TFA group (p = 0.029, < 0.001, < 0.001, respectively). However, there was no significant difference in major adverse cardiac events during hospitalization and after 1 year follow-up between both groups (p = 0.338, 1.000, respectively).
TRA is a useful alternative to TFA in elderly patient with SCCL. The advantages of TRA over TFA include reduced time of bed rest and hospital stay and vascular complications at the puncture site.
球囊无法通过严重钙化的冠状动脉病变(SCCL),有时即使球囊能够通过病变,也无法在高压下打开病变。在这种情况下,经桡动脉途径(TRA)进行旋磨术(RA)的数据有限。本研究的目的是评估经TRA行RA的老年SCCL患者的院内及1年预后。
本回顾性分析纳入了86例连续接受RA的初发SCCL老年患者,在2008年至2013年期间将其分为TRA组(n = 45)和经股动脉途径(TFA,n = 41)组。比较两组的基线特征、院内及1年终点。
与TFA相比,桡动脉途径显著更多地使用6Fr引导导管(p < 0.001)。在TRA组中,1.25mm的磨头尺寸使用率更高,且平均磨头尺寸小于TFA组(p = 0.021)。与TFA组相比,TRA组的血管入路部位并发症、卧床时间和住院时间显著更低(分别为p = 0.029、< 0.001、< 0.001)。然而,两组在住院期间及1年随访后的主要不良心脏事件方面无显著差异(分别为p = 0.338、1.000)。
对于老年SCCL患者,TRA是TFA的一种有用替代方法。TRA相对于TFA的优势包括减少卧床时间和住院时间以及穿刺部位的血管并发症。