在双相介质中使用结构明确的铁（II）PNP钳形配合物对醛进行选择性氢化反应。

Weber Stefan, Brünig Julian, Zeindlhofer Veronika, Schröder Christian, Stöger Berthold, Limbeck Andreas, Kirchner Karl, Bica Katharina

Institute of Applied Synthetic Chemistry Vienna University of Technology Getreidemarkt 9/163-AC Wien A-1060 Austria.

Department of Computational Biological Chemistry University of Vienna Faculty of Chemistry Währingerstrasse 17 Wien A-1090 Austria.

ChemCatChem. 2018 Oct 9;10(19):4386-4394. doi: 10.1002/cctc.201800841. Epub 2018 Aug 22.

A biphasic process for the hydrogenation of aldehydes was developed using a well-defined iron (II) PNP pincer complex as model system to investigate the performance of various ionic liquids. A number of suitable hydrophobic ionic liquids based on the N(Tf) anion were identified, allowing to immobilize the iron (II) catalyst in the ionic liquid layer and to facilitate the separation of the desired alcohols. Further studies showed that targeted Brønsted basic ionic liquids can eliminate the need of an external base to activate the catalyst.

我们开发了一种醛加氢的双相过程，使用一种定义明确的铁（II）PNP钳形配合物作为模型体系来研究各种离子液体的性能。我们确定了许多基于N(Tf) 阴离子的合适疏水性离子液体，这使得铁（II）催化剂能够固定在离子液体层中，并有助于所需醇类的分离。进一步的研究表明，目标布朗斯特碱性离子液体可以消除使用外部碱来活化催化剂的需求。