Peralta Santiago, Campbell Robert D, Fiani Nadine, Kan-Rohrer Kimi H, Verstraete Frank J M
J Am Vet Med Assoc. 2018 Dec 1;253(11):1445-1451. doi: 10.2460/javma.253.11.1445.
OBJECTIVE To determine and identify variables associated with outcomes of surgical repair of congenital palatal defects in dogs. DESIGN Retrospective case series with nested observational study. ANIMALS 26 dogs that underwent surgical repair of congenital palatal defects at 2 veterinary teaching hospitals from 2007 to 2016. PROCEDURES Data were collected from medical records regarding dog age and body weight at the time of surgical defect repair, prior surgical history, skull type (brachycephalic, mesocephalic, or dolichocephalic), surgical technique used for defect repair, and defect severity. Functional outcome as well as frequency and location of oronasal fistula (ONF) formation were recorded. These outcomes were compared among various groups. RESULTS Surgical defect repair achieved functional success in 22 of the 26 (85%) dogs. An ONF formed after initial repair in 13 (50%) dogs, and the most common location was the hard palate. Hard palate ONF formation was more common in dogs > 8 months of age at the time of initial repair; ONF at the junction between the hard and soft palates was more common in dogs > 8 months of age at the time of initial repair and in dogs with a history of failed surgical repair. An unsuccessful functional outcome was more common in dogs weighing < 1 kg (2.2 lb) at the time of initial repair. CONCLUSIONS AND CLINICAL RELEVANCE Patient age, patient size, and defect characteristics should be taken into consideration when planning and assessing prognoses for surgical repair of congenital palatal defects in dogs.
目的 确定并识别与犬先天性腭裂手术修复结局相关的变量。 设计 带有嵌套观察性研究的回顾性病例系列。 动物 2007年至2016年在2家兽医教学医院接受先天性腭裂手术修复的26只犬。 程序 从病历中收集有关手术缺损修复时犬的年龄和体重、既往手术史、头骨类型（短头型、中头型或长头型）、用于缺损修复的手术技术以及缺损严重程度的数据。记录功能结局以及口鼻瘘（ONF）形成的频率和位置。对不同组之间的这些结局进行比较。 结果 26只犬中有22只（85%）手术缺损修复获得功能成功。13只（50%）犬在初次修复后形成了ONF，最常见的位置是硬腭。初次修复时年龄>8个月的犬硬腭ONF形成更常见；初次修复时年龄>8个月且有手术修复失败史的犬在硬腭与软腭交界处的ONF更常见。初次修复时体重<1 kg（2.2磅）的犬功能结局不成功更常见。 结论及临床意义 在规划和评估犬先天性腭裂手术修复的预后时，应考虑患者年龄、患者体型和缺损特征。
