Suppr超能文献

泌尿外科慢性盆腔疼痛综合征患者的症状持续时间与疼痛严重程度、非泌尿系统综合征及心理健康症状无关:慢性盆腔疼痛网络研究的多学科方法

Symptom Duration in Patients With Urologic Chronic Pelvic Pain Syndrome is not Associated With Pain Severity, Nonurologic Syndromes and Mental Health Symptoms: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Network Study.

作者信息

Rodríguez Larissa V, Stephens Alisa J, Clemens J Quentin, Buchwald Dedra, Yang Claire, Lai Henry H, Krieger John N, Newcomb Craig, Bradley Cate S, Naliboff Bruce

机构信息

Departments of Urology and Obstetrics and Gynecology, Institute of Urology, University of Southern California, Los Angeles, CA.

Data Coordinating Core, Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

出版信息

Urology. 2019 Feb;124:14-22. doi: 10.1016/j.urology.2018.11.015. Epub 2018 Nov 16.

Abstract

OBJECTIVE

To evaluate if patients with urologic chronic pelvic pain syndromes (UCPPS) with longer duration of symptoms experience more severe pain and urologic symptoms, higher rates of chronic overlapping pain conditions (COPC) and psychosocial comorbidities than those with a more recent onset of the condition. We evaluated cross-sectional associations between UCPPS symptom duration and (1) symptom severity, (2) presence of COPC, and (3) mental health comorbidities.

METHODS

We analyzed baseline data from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain. Symptom severity, COPC, and mental health comorbidities were compared between patients with symptom duration of < 2 vs ≥ 2 years. Symptom severity was assessed by the Genitourinary Pain Index, the Interstitial Cystitis Symptom and Problem Index, and Likert scales for pelvic pain, urgency, and frequency. Depression and anxiety were evaluated with the Hospital Anxiety and Depression Scale and stress with the Perceived Stress Scale.

RESULTS

Males (but not females) with UCPPS symptom duration ≥2 years had more severe symptoms than those with <2 years. Participants with short (<2 years) and longer (≥2 years) symptom duration were as likely to experience COPC.

CONCLUSION

Longer UCPPS symptom duration was associated with more severe symptoms only in limited patient subpopulations. Symptom duration was not associated with risk for COPC or mental health comorbidities. Females with longer UCPPS duration had decreased distress, but the association was largely attributable to age.

摘要

目的

评估与症状近期发作的患者相比,症状持续时间较长的泌尿生殖系统慢性盆腔疼痛综合征(UCPPS)患者是否经历更严重的疼痛和泌尿系统症状、更高的慢性重叠疼痛病症(COPC)发生率及心理社会共病率。我们评估了UCPPS症状持续时间与(1)症状严重程度、(2)COPC的存在情况以及(3)心理健康共病之间的横断面关联。

方法

我们分析了慢性盆腔疼痛研究多学科方法的基线数据。比较了症状持续时间<2年与≥2年的患者之间的症状严重程度、COPC和心理健康共病情况。症状严重程度通过泌尿生殖系统疼痛指数、间质性膀胱炎症状与问题指数以及盆腔疼痛、尿急和尿频的李克特量表进行评估。使用医院焦虑抑郁量表评估抑郁和焦虑,使用感知压力量表评估压力。

结果

UCPPS症状持续时间≥2年的男性(而非女性)比症状持续时间<2年的男性症状更严重。症状持续时间短(<2年)和长(≥2年)的参与者经历COPC的可能性相同。

结论

仅在有限的患者亚组中,较长的UCPPS症状持续时间与更严重的症状相关。症状持续时间与COPC风险或心理健康共病无关。UCPPS持续时间较长的女性痛苦程度降低,但这种关联在很大程度上归因于年龄。

相似文献

5
多学科慢性盆腔痛研究网络(MAPP 研究网络)*:症状模式研究(SPS)的设计与实施。
Neurourol Urodyn. 2020 Aug;39(6):1803-1814. doi: 10.1002/nau.24423. Epub 2020 Jun 23.
6
高血压与泌尿生殖系统慢性盆腔疼痛综合征:MAPP-I 数据分析。
BMC Urol. 2024 Jan 28;24(1):21. doi: 10.1186/s12894-024-01407-w.
9
泌尿科慢性盆腔疼痛综合征:来自 MAPP 研究网络的见解。
Nat Rev Urol. 2019 Mar;16(3):187-200. doi: 10.1038/s41585-018-0135-5.
10
疼痛与泌尿系统症状不应合并为单一评分:MAPP研究网络的心理测量结果
J Urol. 2016 Apr;195(4 Pt 1):949-54. doi: 10.1016/j.juro.2015.11.012. Epub 2015 Nov 14.

引用本文的文献

1
成年慢性盆底疼痛综合征患者的心理弹性:灵活自我调节视角
J Pain. 2025 Jul;32:105439. doi: 10.1016/j.jpain.2025.105439. Epub 2025 May 15.
2
这种疼痛令我抓狂:间质性膀胱炎/膀胱疼痛综合征女性的精神症状。
World J Psychiatry. 2024 Jun 19;14(6):954-984. doi: 10.5498/wjp.v14.i6.954.
3
间质性膀胱炎及其他盆腔疼痛综合征对生活质量的影响。
Front Pain Res (Lausanne). 2023 May 25;4:1149783. doi: 10.3389/fpain.2023.1149783. eCollection 2023.

本文引用的文献

1
间质性膀胱炎/膀胱疼痛综合征的新型研究方法:超越膀胱的思考
Transl Androl Urol. 2015 Oct;4(5):524-33. doi: 10.3978/j.issn.2223-4683.2015.08.01.
2
英国和荷兰成年患者的两个临床队列中基于慢性疲劳综合征(CFS)症状的表型。
J Psychosom Res. 2016 Feb;81:14-23. doi: 10.1016/j.jpsychores.2015.12.006. Epub 2015 Dec 23.
4
MAPP研究队列中男性和女性基线泌尿系统症状的比较。
J Urol. 2015 May;193(5):1554-8. doi: 10.1016/j.juro.2014.11.016. Epub 2014 Nov 13.
6
MAPP研究网络:设计、患者特征与运作
BMC Urol. 2014 Aug 1;14:58. doi: 10.1186/1471-2490-14-58.
7
9
间质性膀胱炎/膀胱疼痛综合征中对机械刺激的节段性痛觉过敏:中枢敏化的证据
J Urol. 2014 May;191(5):1294-9. doi: 10.1016/j.juro.2013.11.099. Epub 2013 Dec 6.
10
间质性膀胱炎/膀胱疼痛综合征与非膀胱疾病的时间顺序。
Urology. 2012 Dec;80(6):1227-31. doi: 10.1016/j.urology.2012.06.059.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验