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颈椎手术后 3 个月重返工作岗位的预测模型和诺莫图:来自质量结果数据库的分析。

A predictive model and nomogram for predicting return to work at 3 months after cervical spine surgery: an analysis from the Quality Outcomes Database.

机构信息

1Department of Orthopedic Surgery and Neurological Surgery, Vanderbilt Spine Center, Vanderbilt University Medical Center, Nashville, Tennessee.

2Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

Neurosurg Focus. 2018 Nov 1;45(5):E9. doi: 10.3171/2018.8.FOCUS18326.

DOI:10.3171/2018.8.FOCUS18326
PMID:30453462
Abstract

OBJECTIVEBack pain and neck pain are two of the most common causes of work loss due to disability, which poses an economic burden on society. Due to recent changes in healthcare policies, patient-centered outcomes including return to work have been increasingly prioritized by physicians and hospitals to optimize healthcare delivery. In this study, the authors used a national spine registry to identify clinical factors associated with return to work at 3 months among patients undergoing a cervical spine surgery.METHODSThe authors queried the Quality Outcomes Database registry for information collected from April 2013 through March 2017 for preoperatively employed patients undergoing cervical spine surgery for degenerative spine disease. Covariates included demographic, clinical, and operative variables, and baseline patient-reported outcomes. Multiple imputations were used for missing values and multivariable logistic regression analysis was used to identify factors associated with higher odds of returning to work. Bootstrap resampling (200 iterations) was used to assess the validity of the model. A nomogram was constructed using the results of the multivariable model.RESULTSA total of 4689 patients were analyzed, of whom 82.2% (n = 3854) returned to work at 3 months postoperatively. Among previously employed and working patients, 89.3% (n = 3443) returned to work compared to 52.3% (n = 411) among those who were employed but not working (e.g., were on a leave) at the time of surgery (p < 0.001). On multivariable logistic regression the authors found that patients who were less likely to return to work were older (age > 56-65 years: OR 0.69, 95% CI 0.57-0.85, p < 0.001; age > 65 years: OR 0.65, 95% CI 0.43-0.97, p = 0.02); were employed but not working (OR 0.24, 95% CI 0.20-0.29, p < 0.001); were employed part time (OR 0.56, 95% CI 0.42-0.76, p < 0.001); had a heavy-intensity (OR 0.42, 95% CI 0.32-0.54, p < 0.001) or medium-intensity (OR 0.59, 95% CI 0.46-0.76, p < 0.001) occupation compared to a sedentary occupation type; had workers' compensation (OR 0.38, 95% CI 0.28-0.53, p < 0.001); had a higher Neck Disability Index score at baseline (OR 0.60, 95% CI 0.51-0.70, p = 0.017); were more likely to present with myelopathy (OR 0.52, 95% CI 0.42-0.63, p < 0.001); and had more levels fused (3-5 levels: OR 0.46, 95% CI 0.35-0.61, p < 0.001). Using the multivariable analysis, the authors then constructed a nomogram to predict return to work, which was found to have an area under the curve of 0.812 and good validity.CONCLUSIONSReturn to work is a crucial outcome that is being increasingly prioritized for employed patients undergoing spine surgery. The results from this study could help surgeons identify at-risk patients so that preoperative expectations could be discussed more comprehensively.

摘要

目的

腰痛和颈痛是导致残疾丧失工作能力的最常见原因之一,这给社会带来了经济负担。由于最近医疗保健政策的变化,以患者为中心的结果,包括重返工作岗位,已被医生和医院越来越优先考虑,以优化医疗保健的提供。在这项研究中,作者使用国家脊柱登记处来确定接受颈椎手术的患者在术后 3 个月内重返工作岗位的临床相关因素。

方法

作者从 2013 年 4 月至 2017 年 3 月期间,从 Quality Outcomes Database 登记处查询了接受退行性脊柱疾病颈椎手术的术前在职患者的信息。协变量包括人口统计学、临床和手术变量,以及基线患者报告的结果。使用多重插补处理缺失值,使用多变量逻辑回归分析识别与更高的重返工作岗位几率相关的因素。使用 200 次迭代的自举重采样(Bootstrap resampling)评估模型的有效性。使用多变量模型的结果构建了一个列线图。

结果

共分析了 4689 例患者,其中 82.2%(n=3854)在术后 3 个月内重返工作岗位。在先前在职且工作的患者中,89.3%(n=3443)重返工作岗位,而在手术时在职但不工作(例如休假)的患者中,有 52.3%(n=411)重返工作岗位(p<0.001)。多变量逻辑回归显示,不太可能重返工作岗位的患者年龄较大(年龄>56-65 岁:OR 0.69,95%CI 0.57-0.85,p<0.001;年龄>65 岁:OR 0.65,95%CI 0.43-0.97,p=0.02);在职但不工作(OR 0.24,95%CI 0.20-0.29,p<0.001);从事兼职工作(OR 0.56,95%CI 0.42-0.76,p<0.001);工作强度较高(OR 0.42,95%CI 0.32-0.54,p<0.001)或中等强度(OR 0.59,95%CI 0.46-0.76,p<0.001),而非久坐型职业类型;有工人赔偿(OR 0.38,95%CI 0.28-0.53,p<0.001);基线时颈部残疾指数评分较高(OR 0.60,95%CI 0.51-0.70,p=0.017);更有可能出现脊髓病(OR 0.52,95%CI 0.42-0.63,p<0.001);融合的节段较多(3-5 个节段:OR 0.46,95%CI 0.35-0.61,p<0.001)。作者使用多变量分析,然后构建了一个预测重返工作岗位的列线图,发现其曲线下面积为 0.812,具有良好的有效性。

结论

重返工作岗位是一个重要的结果,对于接受脊柱手术的在职患者来说,这一结果的优先级正在不断提高。这项研究的结果可以帮助外科医生识别高风险患者,以便更全面地讨论术前预期。

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