三氯生，一种常见的抗菌成分，对肠道微生物群和肠道健康的影响。
Triclosan, a common antimicrobial ingredient, on gut microbiota and gut health.
机构信息
a Department of Food Science and Molecular and Cellular Biology Program , University of Massachusetts , Amherst , MA , USA.
出版信息
Gut Microbes. 2019;10(3):434-437. doi: 10.1080/19490976.2018.1546521. Epub 2018 Nov 20.
Abstract
Triclosan (TCS) is an antimicrobial compound incorporated into more than 2,000 consumer products. This compound is frequently detected in the human body and causes ubiquitous contamination in the environment, raising concerns about its impact on human health and environmental pollution. Our recent research showed that exposure to TCS exaggerates colonic inflammation and exacerbates development of colitis-associated colon tumorigenesis, via gut microbiome-dependent mechanisms. In this review, we discussed recent research about TCS, as well as other consumer antimicrobials, on the gut microbiome and gut health.
摘要
三氯生（TCS）是一种抗菌化合物，被加入到 2000 多种消费产品中。这种化合物经常在人体内被检测到，并在环境中造成无处不在的污染，引起了人们对其对人类健康和环境污染影响的关注。我们最近的研究表明，三氯生通过肠道微生物组依赖的机制，加剧了结肠炎症，并加重了结肠炎相关的结肠癌发生。在这篇综述中，我们讨论了三氯生和其他消费性抗菌剂对肠道微生物组和肠道健康的最新研究。
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