现代肺结核萎陷疗法

Modern Collapse Therapy for Pulmonary Tuberculosis.

作者信息

Krasnov Denis V, Skluev Sergey V, Petrova Yana K, Skvortsov Dmitry A, Krasnov Vladimir A, Felker Irina G, Grischenko Nikolay

机构信息

Surgical Department, Federal State Budgetary Institution, Novosibirsk Tuberculosis Research Institute, Ministry of Health of the Russian Federation, Okhotskaya Street 81a, Novosibirsk 630040, Russian Federation; Tuberculosis Department, Novosibirsk State Medical University, Faculty of Professional Development and Professional Retraining of Doctors, Krasnyi Prospect 52, Novosibirsk 630091, Russian Federation.

Endoscopy Department, Federal State Budgetary Institution, Novosibirsk Tuberculosis Research Institute, Ministry of Health of the Russian Federation, Okhotskaya Street 81a, Novosibirsk 630040, Russian Federation; Treatment Faculty, Tuberculosis Department, Novosibirsk State Medical University, Krasnyi Prospect 52, Novosibirsk 630091, Russian Federation.

出版信息

Thorac Surg Clin. 2019 Feb;29(1):47-58. doi: 10.1016/j.thorsurg.2018.09.005.

DOI:10.1016/j.thorsurg.2018.09.005

PMID:30454921

Abstract

Multidrug-resistant tuberculosis (TB), extensively drug-resistant TB, and TB-human immunodeficiency virus (HIV) coinfection require a special approach in anti-TB treatment. Most patients cannot be successfully cured by conventional chemotherapy alone. They need a modern approach using minimally invasive therapeutic and surgical techniques. The novel approaches of collapse therapy techniques and minimally invasive osteoplastic thoracoplasty increase the effectiveness of complex anti-TB therapy. Achieving the required selective collapse of lung tissue in destructive pulmonary TB, especially in cases of drug resistance and/or HIV coinfection, leads to bacteriologic conversion, cavity closure, and successful cure.

摘要

耐多药结核病、广泛耐药结核病以及结核病与人类免疫缺陷病毒（HIV）合并感染在抗结核治疗中需要采用特殊方法。大多数患者仅通过传统化疗无法成功治愈。他们需要采用微创治疗和手术技术的现代方法。萎陷治疗技术和微创骨成形胸廓成形术等新方法提高了综合抗结核治疗的效果。在破坏性肺结核中，尤其是在耐药和/或合并HIV感染的情况下，实现肺组织所需的选择性萎陷可导致细菌学转阴、空洞闭合并成功治愈。