Mamoun Chtioui, Houda Fagouri
Centre Médico-chirurgical, Université Ibn Zohr, Agadir, Maroc.
Service de Gynécologie-Obstétrique, Hôpital Militaire d'Instruction, Rabat, Maroc.
Pan Afr Med J. 2018 Jun 27;30:184. doi: 10.11604/pamj.2018.30.184.14262. eCollection 2018.
The diagnosis of splenic infarction is rarely reported in pregnant women. Current incidence of splenic infarction, especially during infectious endocardites as well as diagnostic methods used are poorly specified in the literature. We here report the case of a 26-year old woman with no particular previous history or cardiovascular risk factor who, at the end 14 weeks of amenorrhea, presented to the Emergency Department with febrile syndrome evolving over 10 days and abdominal pain of recent onset at the level of the left hypochondre. Clinical examination showed febrile patient with a temperature of 39.5°C, tenderness of the left hypochondre and panaritium at the level of the palm of the left hand and of the sole of the foot. Gynecological examination was strictly normal. Given this clinical picture, abdominal ultrasound showed mediosplenic anechoic area with hilar apex and with peripheral edges, suggesting splenic infarct. Etiological assessment included echocardiography showing thickened and remodeled oslerian graft on the mitral valve with large valve vegetation and MI grade II. Blood cultures were performed during the febrile peaks and were positive for golden staph. Patient's evolution was marked by the occurrence of large ischemic stroke and worsening of neurological condition, leading to death after several systemic emboli. Splenic infarction in a pregnant woman is very rare. However, clinical and radiological examination of the spleen must be performed in patients with acute abdominal pain of the left hypochondre. In the present case, pain of the left hypochondre associated with fever and Osler's false whitlow was found to be splenic infarction associated with infectious endocarditis. Probabilistic antibiotic therapy as first-line therapy is justified during infective endocarditis and should be secondarily adapted to the bacteriological results. Although rare, splenic infarction can have severe consequences such as abscesses or rupture, which must encourage vigilance.
孕妇脾梗死的诊断鲜有报道。目前脾梗死的发病率,尤其是在感染性心内膜炎期间的发病率,以及所使用的诊断方法,在文献中都缺乏明确说明。我们在此报告一例26岁女性病例,该女性既往无特殊病史或心血管危险因素,在停经14周时因发热综合征持续10天且近期出现左上腹疼痛而就诊于急诊科。临床检查显示患者发热,体温39.5°C,左上腹压痛,左手掌和脚底有脓性指头炎。妇科检查完全正常。鉴于此临床表现,腹部超声显示脾中部有一个无回声区,有肝门顶点和周边边缘,提示脾梗死。病因评估包括超声心动图显示二尖瓣上增厚且重塑的奥斯勒氏赘生物,伴有大的瓣膜赘生物和心肌梗死II级。在发热高峰期间进行了血培养,结果显示金黄色葡萄球菌阳性。患者的病情发展以发生大面积缺血性中风和神经状况恶化为特征,在多次全身性栓塞后死亡。孕妇脾梗死非常罕见。然而,对于左上腹急性腹痛的患者,必须进行脾脏的临床和影像学检查。在本病例中,发现左上腹疼痛伴发热和奥斯勒氏假指炎是与感染性心内膜炎相关的脾梗死。在感染性心内膜炎期间,作为一线治疗的经验性抗生素治疗是合理的,其次应根据细菌学结果进行调整。尽管罕见,但脾梗死可能会产生严重后果,如脓肿或破裂,这必须引起警惕。