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选择性胆囊切除术作为转移性乳腺癌的一种罕见表现。

Elective cholecystectomy as a rare presentation of metastatic breast cancer.

作者信息

Magalhães Joana S, Matos Leonor, Santos Teresa, Nora Mário

机构信息

Surgical Department, Centro Hospitalar Entre Douro e Vouga, E.P.E., Santa Maria da Feira, Portugal.

出版信息

J Surg Case Rep. 2018 Nov 13;2018(11):rjy301. doi: 10.1093/jscr/rjy301. eCollection 2018 Nov.

Abstract

Cholecystectomy leads, occasionally, to the diagnosis of subclinical primary carcinomas and rarely metastatic tumors. The authors report the diagnosis of gallbladder metastasis after an elective cholecystectomy for symptomatic cholelithiasis. Histological examination disclosed a metastasis from a lobular breast carcinoma. Authors found no more than 25 case reports of breast cancer metastasis in English literature. Of those, only one reports first diagnosis after elective cholecystectomy with no radiological or macroscopic signs of malignancy. Rare clinical presentations, as in this case, should always be kept in mind specially in high volume centers. These rare presentations lack good quality evidence and challenge the best standard treatment regimen available. Multidisciplinary assessment is the key to maximize the risk/benefit of different treatment modalities. In this case report, although curative surgery was attempted, progression disease was typical of an advance staged disease.

摘要

胆囊切除术偶尔会导致亚临床原发性癌的诊断,很少会发现转移性肿瘤。作者报告了一例因有症状的胆结石行择期胆囊切除术后诊断为胆囊转移瘤的病例。组织学检查显示为小叶型乳腺癌转移。作者在英文文献中发现不超过25例乳腺癌转移的病例报告。其中,只有一例报告是在择期胆囊切除术后首次诊断,且无恶性肿瘤的影像学或肉眼可见迹象。像本例这样罕见的临床表现,在高流量中心尤其应始终牢记。这些罕见的表现缺乏高质量证据,对现有的最佳标准治疗方案构成挑战。多学科评估是最大化不同治疗方式风险/获益的关键。在本病例报告中,尽管尝试了根治性手术,但疾病进展是晚期疾病的典型表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdc1/6234511/1e0edf63d1a4/rjy301f01.jpg

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