*Department of Emergency Medicine,St. Paul's Hospital,Vancouver, BC.
†Division of Infectious Diseases,St. Michael's Hospital,Toronto, ON.
CJEM. 2019 Jan;21(1):21-25. doi: 10.1017/cem.2018.462. Epub 2018 Nov 20.
The incidence of HIV infections in Canada has increased yearly since 2014. New cases of HIV have resulted almost exclusively from non-occupational exposures, including sexual contact and needle sharing. Appropriate HIV post-exposure prophylaxis is under-prescribed to patients who present to the emergency department after a high-risk exposure. In November of 2017, a Canadian guideline on HIV pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP) was published. The guideline presents a standardized, evidence-based approach to assessing risk for HIV transmission and prescribing HIV prophylaxis. This summary highlights the key points from the guideline that are relevant to the practice of emergency medicine in Canada.
自 2014 年以来,加拿大的 HIV 感染发病率逐年上升。新的 HIV 感染病例几乎完全来自非职业暴露,包括性接触和共用针头。在发生高危接触后到急诊就诊的患者,适当的 HIV 暴露后预防(PEP)的处方不足。2017 年 11 月,加拿大发布了一份关于 HIV 暴露前预防(PrEP)和非职业性暴露后预防(nPEP)的指南。该指南提出了一种标准化、基于证据的方法来评估 HIV 传播风险和开具 HIV 预防药物。本摘要重点介绍了与加拿大急诊医学实践相关的指南中的关键点。