Department of Pulmonary and Critical Care Medicine, Marmara University School of Medicine, Istanbul, Turkey.
Department Internal Medicine Division of Geriatrics, Marmara University School of Medicine, Istanbul, Turkey.
Aging Male. 2020 Dec;23(5):507-512. doi: 10.1080/13685538.2018.1538337. Epub 2018 Nov 20.
Complication rates are low and endobronchial ultrasound guided needle aspiration (EBUS-TBNA) is generally regarded as a safe procedure, but there is a very limited number of studies evaluating the efficacy and safety of the procedure in advanced ages. The aim of this study is to assess the safety and performance outcomes of EBUS-TBNA in elderly.
It was a retrospective observational study; patients who received EBUS-TBNA between September 2016 and January 2018 were evaluated. We analyzed patient's characteristics, doses of midazolam, and lidocaine used, regions of lymph node biopsies, and complications. Also, functionality and general physical status of patients over 65 years of age were evaluated.
During study period 132 cases of EBUS-TBNA were evaluated. 39 (29.5%) cases were aged 70 years, and over. There were more comorbidities in older group. Performance status of older group was worse. Furthermore, when evaluated according to American College of Cardiology (ACC)/American Heart Association (AHA) and American Society of Anesthesiologists (ASA), the older group was found to be composed of the riskier patients. When patients aged between 65 and 69, and over 70 compared, older patient's Barthel, EQ 5-D, SGA, and G8 scores were found to be worse. Despite that, there was no difference in the frequency, and types of complications between both groups. Diagnostic performance was not different between age groups.
Independent from comorbidities, general health status, and functionality EBUS-TBNA procedure in 70-year-old and over patients is a safe minimally invasive procedure.
并发症发生率低，经支气管超声引导针吸活检（EBUS-TBNA）通常被认为是一种安全的操作，但评估该操作在高龄患者中疗效和安全性的研究非常有限。本研究旨在评估 EBUS-TBNA 在老年患者中的安全性和操作结果。
这是一项回顾性观察研究；评估了 2016 年 9 月至 2018 年 1 月期间接受 EBUS-TBNA 的患者。我们分析了患者的特征、咪达唑仑和利多卡因的剂量、淋巴结活检的区域以及并发症。此外，还评估了 65 岁以上患者的功能和一般身体状况。
在研究期间，评估了 132 例 EBUS-TBNA 病例。39 例（29.5%）年龄在 70 岁及以上。老年组有更多的合并症。老年组的表现状态更差。此外，根据美国心脏病学会（ACC）/美国心脏协会（AHA）和美国麻醉医师学会（ASA）进行评估时，发现老年组患者的风险更高。当比较 65-69 岁和 70 岁以上的患者时，发现老年患者的巴氏量表、EQ-5D、SGA 和 G8 评分更差。尽管如此，两组之间的并发症频率和类型并无差异。两组的诊断性能无差异。
无论合并症、一般健康状况和功能如何，70 岁及以上患者的 EBUS-TBNA 操作都是一种安全的微创操作。
