Marín Gabriel Miguel Á, Ortiz Movilla Roberto, Muñoz Labián Carmen, Sánchez Mateos Miguel F, Sánchez Salmador Rebeca
Departamento de Pediatría, Unidad Neonatal, Hospital Universitario Puerta de Hierro Majadahonda, España.
Departamento de Pediatría, Universidad Autónoma de Madrid, España.
Arch Argent Pediatr. 2018 Dec 1;116(6):e762-e764. doi: 10.5546/aap.2018.e762.
Enoxaparin is a low molecular weight heparin used in the neonatal period. It requires less monitoring than standard or unfractionated heparin, although current knowledge about its dose and therapeutic levels in neonates is scarce. In addition, there is very limited information about the management of overdose in this age group. We present the first case published in Spanish of a neonate who accidentally received a dose of enoxaparin ten times higher than the therapeutic one and an isolated dose of protamine to reverse its effect.