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非囊性纤维化支气管扩张症的管理

Management of Non-Cystic Fibrosis Bronchiectasis.

作者信息

Dull Stacey K, Havlat Brooke D, Sanley Michael J, Malesker Mark A

出版信息

Consult Pharm. 2018 Nov 1;33(11):658-666. doi: 10.4140/TCP.n.2018.658..

Abstract

The purpose of this report is to describe the case of a 43-year-old male with asthma who was hospitalized for an exacerbation of non-cystic fibrosis bronchiectasis (NCFB), a chronic lung disease that is characterized by dilation of the airways, persistent cough, chronic sputum production, and recurrent respiratory infections. He was treated with oral and inhaled antibiotics, inhaled bronchodilators, and aggressive airway-clearance techniques including nebulized 7% sodium chloride, flutter valve, and high-frequency chest wall oscillation. Community pharmacy, nursing facility pharmacy, consultant pharmacy practice. As the number of patients diagnosed with NCFB continues to increase, it is crucial to recognize that specific guidance for management of NCFB is warranted, as treatment responses differ from cystic fibrosis bronchiectasis or chronic obstructive pulmonary disease. It is important for pharmacists to understand the pharmacologic and nonpharmacologic treatments for NCFB to better assist physicians and patients and improve therapeutic outcomes.

摘要

本报告旨在描述一名43岁哮喘男性患者的病例,该患者因非囊性纤维化支气管扩张症(NCFB)急性加重而住院,NCFB是一种慢性肺部疾病,其特征为气道扩张、持续咳嗽、慢性咳痰及反复呼吸道感染。他接受了口服及吸入抗生素、吸入支气管扩张剂治疗,并采用了包括雾化7%氯化钠、颤动阀和高频胸壁振荡在内的积极气道清理技术。社区药房、护理机构药房、咨询药房实践。随着被诊断为NCFB的患者数量持续增加,认识到有必要针对NCFB的管理提供具体指导至关重要,因为其治疗反应与囊性纤维化支气管扩张症或慢性阻塞性肺疾病不同。药剂师了解NCFB的药物及非药物治疗方法对于更好地协助医生和患者并改善治疗效果很重要。

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