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超声引导下细针穿刺细胞学检查后发生的皮肤植入性结核

Implantation cutaneous tuberculosis after ultrasound-guided fine needle aspiration cytology.

作者信息

Dutta Usha, Shrestha Deepa, Sharma Amit, Gupta Parikshaa, Das Ashim, Srinivasan Radhika, Anupam Lal, Sharma Vishal, Rana Surinder Singh

机构信息

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

BJR Case Rep. 2016 Jul 28;2(3):20150393. doi: 10.1259/bjrcr.20150393. eCollection 2016.

Abstract

A 45-year-old female presented with recurrent biliary pain, fever, anorexia and weight loss of 3 months duration. She was on highly active antiretroviral therapy for underlying human immunodeficiency virus infection for the past 5 months. Clinical examination revealed a 3-cm firm hepatomegaly. Investigations suggested mild anaemia, elevated erythrocyte sedimentation rate, deranged liver function tests, Mantoux test of 25 mm and CD4 count of 417 cells μl. Ultrasonography revealed mild central intrahepatic biliary radical dilatation with a dilated common bile duct and multiple periportal and peripancreatic lymph nodes. Ultrasound-guided fine needle aspiration cytology (FNAC) from the periportal lymph node was performed twice. Both were reported as only bloody aspirate. The patient developed an erythematous tender skin nodule at the site of insertion of the FNAC needle 15 days after the second FNAC procedure. An excision biopsy of the nodule showed ill-formed epithelioid cell granulomas with acid-fast bacilli, indicating tuberculosis. The patient was started on antitubercular therapy with complete response.

摘要

一名45岁女性,出现反复胆绞痛、发热、厌食及体重减轻3个月。在过去5个月,她因潜在的人类免疫缺陷病毒感染接受高效抗逆转录病毒治疗。临床检查发现肝脏肿大3厘米且质地坚硬。检查提示轻度贫血、红细胞沉降率升高、肝功能检查结果异常、结核菌素试验为25毫米以及CD4细胞计数为417个/微升。超声检查显示肝内中央胆管轻度扩张,胆总管扩张,肝门周围及胰周有多个淋巴结。对肝门周围淋巴结进行了两次超声引导下细针穿刺抽吸细胞学检查(FNAC)。两次检查报告均仅为血性抽吸物。在第二次FNAC操作15天后,患者在FNAC针穿刺部位出现一个红斑性压痛性皮肤结节。对该结节进行切除活检,显示有含抗酸杆菌的形态不佳的上皮样细胞肉芽肿,提示为结核病。患者开始接受抗结核治疗,病情完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a3/6243350/77c9fb06bfde/bjrcr.20150393.g001.jpg

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