Makis William, Probst Stephan
Department of Diagnostic Imaging, Cross Cancer Institute, Edmonton, AB, Canada.
Department of Nuclear Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada.
BJR Case Rep. 2016 Jul 28;2(3):20150440. doi: 10.1259/bjrcr.20150440. eCollection 2016.
Fibrous dysplasia accounts for approximately 7% of benign bone tumours and is a developmental disorder of unknown aetiology. Malignant transformation has been reported in 0.4% of all cases of fibrous dysplasia, and the use of F-fludeoxyglucose positron emission tomography/CT scan in the evaluation of malignant transformation has not yet been established. A 72-year-old male with a long-standing history of polyostotic fibrous dysplasia presented with chest and back pain and was evaluated with a Tc-methylene diphosphonate bone scan as well as an F-fludeoxyglucose positron emission tomography/CT scan to define the extent of bone involvement and assess for possible malignant transformation. We present the imaging findings as well as the long-term follow-up of this case.
骨纤维发育不良约占良性骨肿瘤的7%，是一种病因不明的发育性疾病。据报道，在所有骨纤维发育不良病例中，恶变率为0.4%，而氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）在评估恶变方面的应用尚未确立。一名72岁男性，有长期多骨型骨纤维发育不良病史，出现胸痛和背痛，接受了锝-亚甲基二膦酸盐骨扫描以及氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描，以确定骨受累范围并评估是否可能发生恶变。我们展示了该病例的影像学表现及长期随访情况。
