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一名免疫抑制的肾移植患者发生脑和肺淋巴瘤样肉芽肿病以及EBV阳性食管溃疡,在接受利妥昔单抗治疗后通过系列MRI和F-FDG PET/CT进行分期及随访。

Cerebral and pulmonary lymphomatoid granulomatosis and EBV positive oesophageal ulcer in an immunosuppressed renal transplant patient staged and followed with serial MRI and F-FDG PET/CT after rituximab therapy.

作者信息

Makis William, Deschenes Jean

机构信息

Department of Diagnostic Imaging, Cross Cancer Institute, Edmonton, AB, Canada.

Department of Pathology, Cross Cancer Institute, Edmonton, AB, Canada.

出版信息

BJR Case Rep. 2016 Jul 28;2(3):20150503. doi: 10.1259/bjrcr.20150503. eCollection 2016.

Abstract

Lymphomatoid granulomatosis is a rare Epstein-Barr virus-related lymphoproliferative disorder. We describe a case of a 42-year-old female with lupus nephritis and immunosuppression post renal transplant, who was diagnosed with central nervous system and lung lymphomatoid granulomatosis, as well as an Epstein-Barr virus-positive oesophageal ulcer, and was staged and followed up long term with multiple F-fludeoxyglucose positron emission tomography/CT scans and brain MRIs after achieving a complete metabolic response with rituximab.

摘要

淋巴瘤样肉芽肿病是一种罕见的与爱泼斯坦-巴尔病毒相关的淋巴增殖性疾病。我们描述了一例42岁女性患者,她患有狼疮性肾炎且肾移植后处于免疫抑制状态,被诊断为中枢神经系统和肺部淋巴瘤样肉芽肿病,以及爱泼斯坦-巴尔病毒阳性的食管溃疡,在使用利妥昔单抗实现完全代谢缓解后,通过多次F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描和脑部磁共振成像进行了长期分期和随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a461/6243357/b4dcec925bed/bjrcr.20150503.g001.jpg

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