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鼻腔副神经节瘤：从放射学和病理学角度的鉴别诊断

Nasal paraganglioma: differential diagnosis from a radiologic and pathologic perspective.

作者信息

Tolman Christine J, Stam Olga Cg

机构信息

Department of Radiology, Medisch Centrum Haaglanden, The Hague, Netherlands.

Department of Pathology, Academisch Medisch Centrum, Amsterdam, Netherlands.

出版信息

BJR Case Rep. 2016 Nov 2;2(4):20160050. doi: 10.1259/bjrcr.20160050. eCollection 2016.

DOI:10.1259/bjrcr.20160050
PMID:30460037
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6243326/
Abstract

A 33-year-old Asian male presented with spontaneous nosebleeds and olfactory sense problems for the past several years. CT scan and MRI demonstrated a large soft tissue mass in the nasal cavity and paranasal sinus with avid and homogeneous contrast enhancement, focal osseous destruction and a non-enhancing cyst at the intracranial tumour-brain margin. After complete endonasal resection, histopathological examination revealed a paraganglioma. This case highlights the non-specific imaging features of a rare paraganglioma of the anterior skull base and the differential diagnosis from both radiological and pathological perspective.

摘要

一名33岁的亚洲男性在过去几年中出现了自发性鼻出血和嗅觉问题。CT扫描和MRI显示鼻腔和鼻窦有一个大的软组织肿块，造影剂呈强烈且均匀的增强，有局灶性骨质破坏，且在颅内肿瘤-脑边缘有一个无强化的囊肿。经鼻内镜完全切除后，组织病理学检查显示为副神经节瘤。该病例突出了罕见的前颅底副神经节瘤的非特异性影像学特征以及从放射学和病理学角度的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd97/6243326/b1e2307d0f39/bjrcr.20160050.g010.jpg
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本文引用的文献

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BMC Med Imaging. 2016 Feb 1;16:12. doi: 10.1186/s12880-016-0114-3.
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15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma-paraganglioma syndromes characterized by germline SDHB and SDHD mutations.
15年的副神经节瘤研究：以种系SDHB和SDHD突变为特征的嗜铬细胞瘤-副神经节瘤综合征的遗传学及机制
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