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腹腔镜 Roux-en-Y 胃旁路术不分离肠系膜可降低术后并发症风险。

Laparoscopic Roux-en-Y Gastric Bypass Without Division of the Mesentery Reduces the Risk of Postoperative Complications.

机构信息

Department of Surgical and Perioperative Science (Hand and Plastic Surgery), Umeå University, Umeå, Sweden.

Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.

出版信息

Surg Endosc. 2019 Sep;33(9):2858-2863. doi: 10.1007/s00464-018-6581-6. Epub 2018 Nov 20.

Abstract

BACKGROUND

Anastomotic complications after laparoscopic Roux-en-Y gastric bypass (LRYGB) including leaks, ulceration, and stenosis remain a significant cause of post-operative morbidity and mortality. Our objective was to compare two different surgical techniques regarding short-term anastomotic complications.

METHODS

A retrospective analysis of all patients operated with a primary LRYGB from 2006 to June 2015 in one institution, where prospectively collected data from an internal quality registry and medical journals were analyzed.

RESULTS

In total, 2420 patients were included in the analysis. 1016 were operated with a technique where the mesentery was divided during the creation of the Roux-limb (DM-LRYGB) and 1404 were operated with a method where the mesentery was left intact (IM-LRYGB). Leakage in the first 30 days [2.6% vs. 1.1% (p < 0.05)], and ulceration or stenosis occurring during the first 6 months after surgery [5.6% vs. 0.1% (p < 0.05)] was significantly higher in the DM-LRYGB group. Adjusted odds ratio for anastomotic leak was 0.46 (95% CI 0.24-0.87) and for stenosis/ulceration 0.01 (95% CI 0.002-0.09).

CONCLUSION

IM-LRYGB seems to reduce the risk of complications at the anastomosis. A plausible explanation for this is that the blood supply to the anastomosis is compromised when the mesentery is divided.

摘要

背景

腹腔镜 Roux-en-Y 胃旁路术(LRYGB)后的吻合口并发症,包括漏、溃疡和狭窄,仍然是术后发病率和死亡率的重要原因。我们的目的是比较两种不同的手术技术在短期吻合口并发症方面的差异。

方法

对一家机构 2006 年至 2015 年 6 月期间所有接受初次 LRYGB 手术的患者进行回顾性分析,对内部质量登记处和医学期刊中前瞻性收集的数据进行分析。

结果

共纳入 2420 例患者。1016 例采用系膜在 Roux 支创建时被分割的技术(DM-LRYGB),1404 例采用系膜保持完整的方法(IM-LRYGB)。术后 30 天内的漏(2.6%比 1.1%(p<0.05))和术后 6 个月内发生的溃疡或狭窄(5.6%比 0.1%(p<0.05))在 DM-LRYGB 组显著更高。吻合口漏的调整优势比为 0.46(95%可信区间 0.24-0.87),狭窄/溃疡为 0.01(95%可信区间 0.002-0.09)。

结论

IM-LRYGB 似乎降低了吻合口并发症的风险。这一现象的一个可能解释是,当系膜被分割时,吻合口的血液供应受到影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5bd/6684563/df7f8bb4d3fe/464_2018_6581_Fig1_HTML.jpg

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