Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Department of Cardiology, Affiliated Hospital of Hebei University, Baoding, China.
J Med Syst. 2018 Nov 20;43(1):4. doi: 10.1007/s10916-018-1119-y.
We determined the relevance between the TG-to-HDL-C ratio and stent restenosis. Ninety-nine patients with in-stent stenosis (ISR) who were admitted to An Zhen Hospital in Beijing between April 2014 and June 2017 were selected. At the same time, 122 patients with coronary stenosis <50% were selected. All patients were tested for TG, HDL-C, and TG/HDL-C ratio. Optical coherence tomography (OCT) can assess microscopic status in all ISR patients. The proportion of male and Diabetic patients were significantly higher for ISR. There were differences in the prevalence of cigarette smokers among the different tissue types, among which the layered tissue type accounted for the highest proportion. In logistic regression analysis the study showed that male, diabetes mellitus, and the TG/HDL-C ratio are risk factors for ISR. The ISR ROC was 0.725 based on the TG/HDL-C ratio diagnosis. It is related to the degree of coronary stenosis and effective in diagnosing in-stent stenosis in ISR.
我们确定了 TG 与 HDL-C 比值与支架内再狭窄之间的相关性。选取 2014 年 4 月至 2017 年 6 月期间在北京安贞医院就诊的 99 例支架内狭窄（ISR）患者和 122 例冠状动脉狭窄<50%的患者作为对照。所有患者均检测 TG、HDL-C 和 TG/HDL-C 比值。所有 ISR 患者均行光学相干断层扫描（OCT）以评估其微观状态。ISR 患者中男性和糖尿病患者的比例明显更高。不同组织类型的吸烟者比例存在差异，其中分层组织类型占比最高。在 logistic 回归分析中，研究表明男性、糖尿病和 TG/HDL-C 比值是 ISR 的危险因素。基于 TG/HDL-C 比值诊断的 ISR ROC 为 0.725。它与冠状动脉狭窄程度相关，并且在诊断 ISR 中的支架内狭窄方面具有良好的效果。
