Makowiec Kathryn, McCaslin Devin, Hatton Kelsey
Division of Vestibular Sciences, Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Dizziness and Balance Disorders Clinic, Mayo Clinic, Rochester, MN.
J Am Acad Audiol. 2019 Apr;30(4):293-301. doi: 10.3766/jaaa.17093. Epub 2018 Feb 8.
The purpose of this investigation was to evaluate the sensitivity and specificity of the ocular vestibular evoked myogenic potential (oVEMP) using two electrode montages in patients with confirmed unilateral superior semicircular canal dehiscence syndrome (SCDS).
This study evaluated oVEMP response characteristics measured using two different electrode montages from 12 unilateral SCDS ears and 36 age-matched control ears (age range = 23-66). The oVEMP responses were elicited using 500 Hz tone-burst air conduction stimuli presented at an intensity of 95 dB nHL and a rate of 5.1/sec. The two electrode montages used are described as an "infraorbital" montage and a "belly-tendon" montage.
Balance function laboratory embedded in a large, tertiary care otology clinic.
The belly-tendon electrode montage resulted in significantly larger amplitude responses than the infraorbital electrode montage for the ears with SCDS and the normal control ears. For both electrode montages the ear with SCDS exhibited a significantly larger amplitude response, ∼50% larger than the response amplitude from the normal control ear. The belly-tendon montage additionally produced larger median increases in amplitude compared with the infraorbital montage. Specifically, the median increase in oVEMP N1-P1 amplitudes using the belly-tendon montage was 39% greater in control ears, 76% greater in the SCDS ears, and 17% greater in the contralateral SCDS ears.
The belly-tendon electrode montage yields significantly larger oVEMP amplitude responses for participants with SCDS and normal control participants.
本研究旨在评估在确诊为单侧上半规管裂综合征（SCDS）的患者中，使用两种电极组合时眼前庭诱发肌源性电位（oVEMP）的敏感性和特异性。
本研究评估了12只单侧SCDS耳和36只年龄匹配的对照耳（年龄范围 = 23 - 66岁）使用两种不同电极组合测量的oVEMP反应特征。oVEMP反应通过以95 dB nHL的强度和5.1/秒的速率呈现的500 Hz短纯音气导刺激诱发。所使用的两种电极组合分别描述为“眶下”组合和“肌腹-肌腱”组合。
位于大型三级护理耳科诊所内的平衡功能实验室。
对于SCDS耳和正常对照耳，“肌腹-肌腱”电极组合产生的反应幅度明显大于“眶下”电极组合。对于两种电极组合，SCDS耳的反应幅度明显更大，比正常对照耳的反应幅度大50%左右。与“眶下”组合相比，“肌腹-肌腱”组合还产生了更大的幅度中位数增加。具体而言，使用“肌腹-肌腱”组合时，oVEMP N1 - P1幅度在对照耳中的中位数增加大39%，在SCDS耳中大76%，在对侧SCDS耳中大17%。
对于SCDS参与者和正常对照参与者，“肌腹-肌腱”电极组合产生的oVEMP幅度反应明显更大。
