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阿联酋迪拜青少年的代谢综合征归因于低 HDL 水平的高发率:一项横断面研究。

Metabolic syndrome among adolescents in Dubai, United Arab Emirates, is attributable to the high prevalence of low HDL levels: a cross-sectional study.

机构信息

Department of Public Health and Nutrition, College of Natural and Health Sciences, Zayed University, Dubai, United Arab Emirates.

Department of Nutrition and Food Science, Faculty of Agricultural and Food Sciences, American University of Beirut, Beirut, Lebanon.

出版信息

BMC Public Health. 2018 Nov 21;18(1):1284. doi: 10.1186/s12889-018-6215-x.

DOI:10.1186/s12889-018-6215-x
PMID:30463538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6249919/
Abstract

BACKGROUND

Metabolic syndrome (MetS) describes a combination of risk factors that increase the risk of developing chronic diseases. The prevalences of MetS and its risk factors are increasing, especially in the Arab region. A cross-sectional study was carried out to assess the prevalences of MetS and its associated risk factors among adolescents in the United Arab Emirates (UAE).

METHODS

A total of 596 students (308 boys and 288 girls) aged 10 to 15.9 years old were recruited from 14 public secondary schools in Dubai, UAE. Anthropometric and biochemical data were measured.

RESULTS

According to the International Diabetes Federation (IDF) criteria, the prevalence of MetS was 3.7%, and it was more common among boys than girls (12 boys versus 10 girls). MetS was also more likely to be found in students who were obese or overweight than those with normal weight. The most prevalent and significant MetS risk factor was low high-density lipoprotein (HDL) cholesterol levels.

CONCLUSIONS

This study indicates the importance of carrying out further investigations about the constituents of HDL and their atherogenic effects. Additionally, these results strongly recommend setting a consensus for HDL measurement, since small variations in methodologies may lead to substantial deviations in results.

摘要

背景

代谢综合征(MetS)描述了一系列增加慢性病发病风险的危险因素。代谢综合征及其危险因素的患病率正在上升,尤其是在阿拉伯地区。本横断面研究旨在评估阿联酋青少年代谢综合征及其相关危险因素的患病率。

方法

共招募了 596 名 10 至 15.9 岁的学生(男 308 名,女 288 名),他们来自阿联酋迪拜的 14 所公立中学。测量了人体测量学和生化数据。

结果

根据国际糖尿病联合会(IDF)标准,代谢综合征的患病率为 3.7%,且男孩患病率高于女孩(12 名男孩与 10 名女孩)。肥胖或超重的学生比体重正常的学生更有可能出现代谢综合征。最常见且显著的代谢综合征危险因素是低高密度脂蛋白(HDL)胆固醇水平。

结论

本研究表明,进行关于 HDL 组成及其动脉粥样硬化作用的进一步研究非常重要。此外,这些结果强烈建议就 HDL 测量达成共识,因为方法学的微小差异可能导致结果出现显著偏差。

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